Home > 5-HT Receptor & 5-HT Receptor & > Escitalopram Oxalate

Escitalopram Oxalate

草酸右旋西酞普兰,草酸依地普仑

Escitalopram oxalate是选择性5羟色胺重吸收抑制剂（SSRI），Ki为0.89 nM。

目录号
EY1510
EY1510
EY1510
EY1510
纯度
99.57%
99.57%
99.57%
99.57%
规格
5 mg
10 mg
50 mg
100 mg
原价
298
492
691
880
售价
298
492
691
880
库存
现货
现货
现货
现货
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订购
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  • 生物活性

    Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Mnie-Filali O, et al. Encephale, 2007, 33(6), 965-972.

    分子式
    C22H23FN2O5    		 分子量
    414.43    		 CAS号
    219861-08-2    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    86 mg/mL    		 Water
    25 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01814098 Depressive Disorder, Major Drug: Escitalopram Xian-Janssen Pharmaceutical Ltd. Phase 4 2009-07-01 2014-05-30
    NCT01587326 Depression Drug: Escitalopram Beitou Armed Forces Hospital, Taipei, Taiwan 2012-04-01 2012-05-13
    NCT02623231 GBM|Depression Drug: Escitalopram|Drug: placebo Tel-Aviv Sourasky Medical Center Phase 2|Phase 3 2015-12-01 2015-12-02
    NCT01594866 Major Depressive Disorder Drug: escitalopram|Drug: escitalopram Seoul National University Hospital|H. Lundbeck A/S Phase 4 2012-05-01 2015-12-07
    NCT01214044 Depression Drug: placebo/escitalopram Oregon Health and Science University|Forest Laboratories 2008-05-01 2010-10-01
    NCT00825825 Antidepressant Activity in Healthy Volunteers Drug: Escitalopram|Drug: Citalopram|Drug: Placebo Michael Henry, MD|Forest Laboratories|Steward St. Elizabeth's Medical Center of Boston, Inc. Phase 4 2007-05-01 2015-06-16
    NCT01814085 Major Depressive Disorder Drug: Escitalopram Xian-Janssen Pharmaceutical Ltd. Phase 4 2010-02-01 2014-01-02
    NCT01024140 Chronic Posttraumatic Stress Disorder Drug: Escitalopram Northern California Institute of Research and Education 2003-02-01 2009-12-01
    NCT01219686 Unipolar Depression Drug: escitalopram, pindolol|Drug: escitalopram|Drug: escitalopram Markus KOSEL|University Hospital, Geneva|University of Lausanne Hospitals|University Hospital, Basel, Switzerland|H. Lundbeck A/S Phase 2|Phase 3 2010-10-01 2015-05-26
    NCT01149967 Healthy Drug: Citalopram Hydrobromide Dr. Reddy's Laboratories Limited Phase 1 2003-10-01 2010-06-23
    NCT01149980 Healthy Drug: Citalopram Hydrobromide Dr. Reddy's Laboratories Limited Phase 1 2003-10-01 2010-06-23
    NCT02480400 Major Depressive Disorder Drug: Escitalopram|Drug: Escitalopram Abarbanel Mental Health Center|H. Lundbeck A/S 2010-06-01 2015-06-22
    NCT01551225 Irritable Bowel Syndrome|Panic Disorder Drug: Escitalopram Maastricht University Medical Center Phase 4 2012-01-01 2017-01-11
    NCT01244724 Major Depression|Epilepsy Drug: Lexapro Weill Medical College of Cornell University|Forest Laboratories Phase 4 2007-10-01 2015-07-29
    NCT00965497 Major Depression|Multiple Sclerosis|Amyotrophic Lateral Sclerosis Drug: escitalopram University of South Carolina Phase 3 2009-07-01 2011-08-04
    NCT00183677 Depression Drug: Escitalopram Massachusetts General Hospital Phase 4 2003-07-01 2016-11-04
    NCT00227292 Low Back Pain|Depression Drug: Escitalopram|Drug: Placebo Martin-Luther-Universitt Halle-Wittenberg Phase 4 2007-11-01 2014-06-15
    NCT01841125 Alzheimer's Disease Drug: escitalopram|Drug: Placebo Konkuk University Medical Center Phase 4 2011-11-01 2014-08-12
    NCT00902226 Social Anxiety Disorder Drug: Escitalopram H. Lundbeck A/S Phase 4 2009-03-01 2011-05-11
    NCT00902564 Generalized Anxiety Disorder Drug: Escitalopram H. Lundbeck A/S Phase 4 2009-03-01 2011-05-11

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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