Albendazole

阿苯达唑,丙硫咪唑,丙硫苯咪唑,SKF 62979,SKF62979,SKF-62979,

Albendazole属于苯并咪唑类化合物,可抗蠕虫感染。

目录号
EY1413
EY1413
纯度
99.17%
99.17%
规格
100 mg
500 mg
原价
490
780
售价
490
780
库存
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Whittaker SG, et al. Toxicol Appl Pharmacol,?991, 109(1), 73-84.

    分子式
    C12H15N3O2S
    分子量
    265.33
    CAS号
    54965-21-8
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    16 mg/mL
    Water
    <1 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02784743 Lymphatic Filariasis Drug: ''albendazole'' and ''ivermectin'' Centre d'Appui la lutte contre la Maladie|Malaria Research and Training Center, Bamako, Mali|World Health Organization Phase 4 2001-05-01 2016-05-24
    NCT01087099 Infections With Soil-Transmitted Helminths (STH) Drug: Albendazole University Ghent|Ghent University, Faculty of Veterinary Medicine, Dpt of Virology, Parasitology and Immunology, Belgium|World Health Organization|George Washington University|Commonwealth Scientific and Industrial Research Organisation, Australia|University of Nottingham|Queensland Institute of Medical Research Phase 4 2009-01-01 2011-07-30
    NCT02243644 Neurocysticercosis Drug: 7 days of albendazole 15 mg/kg/day|Drug: 28 days of albendazole 15 mg/kg/day All India Institute of Medical Sciences, New Delhi Phase 3 2014-03-01 2015-12-31
    NCT00511004 Lymphatic Filariasis Drug: Albendazole|Drug: Diethylcarbamazine National Institute of Allergy and Infectious Diseases (NIAID)|National Institutes of Health Clinical Center (CC) Phase 2 2007-07-01 2015-07-30
    NCT00755560 Toxocariasis Drug: Albendazole|Drug: Placebo Hospital de Nios R. Gutierrez de Buenos Aires|The Hospital for Sick Children Phase 3 2008-09-01 2016-02-18
    NCT01755637 Helminthiasis Drug: Albendazole GlaxoSmithKline Phase 1 2012-04-01 2013-07-11
    NCT00441285 Neurocysticercosis|Epilepsy Drug: Praziquantel|Drug: Albendazole|Drug: ABZ Placebo|Drug: PZQ Placebo Universidad Peruana Cayetano Heredia|National Institute of Neurological Disorders and Stroke (NINDS) Phase 2|Phase 3 2010-01-01 2015-05-15
    NCT00765024 Chronic Strongyloidiasis Drug: Ivermectin|Drug: ivermectin|Drug: Albendazole Mahidol University|Atlantic Laboratory Ltd Phase 3 2008-07-01 2010-06-18
    NCT01192802 Intestinal Diseases|Helminthiasis Drug: albendazole|Drug: albendazole|Drug: albendazole Albert Schweitzer Hospital Phase 4 2010-08-01 2013-01-23
    NCT01213576 Lymphatic Filariasis Drug: Albendazole 400mg and ivermectin 200mcg/kg|Drug: Albendazole and ivermectin|Drug: Albendazole 400mg and ivermectin 200mcg/kg|Drug: albendazole 800mg and ivermectin 400mcg/kg bi-annually London School of Hygiene and Tropical Medicine|Emory University 2009-01-01 2015-02-26
    NCT02420574 Helminthiasis Drug: albendazole BENDEX|Drug: albendazole OVIS University Ghent 2014-02-01 2015-04-17
    NCT02636803 Helminthiasis Drug: oxfendazole|Drug: albendazole Robert Gilman|Universidad Peruana Cayetano Heredia|Johns Hopkins Bloomberg School of Public Health Phase 2 2017-11-01 2017-03-02
    NCT00002191 Protozoan Infections|HIV Infections Drug: Albendazole SmithKline Beecham|NIH AIDS Clinical Trials Information Service Phase 3 2005-06-23
    NCT01440608 Enteropathy Drug: Albendazole|Drug: Placebo|Dietary Supplement: High-dose Zinc Washington University School of Medicine 2011-10-01 2012-03-02
    NCT02876146 Alveolar Echinococcosis Drug: Benzimidazole Centre Hospitalier Universitaire de Besancon 2012-06-01 2016-08-22
    NCT01975441 Lymphatic Filariasis Drug: Diethylcarbamazine|Drug: Albendazole|Drug: Ivermectin University Hospitals Cleveland Medical Center Phase 2 2014-05-01 2016-10-11
    NCT00659997 Ascariasis|Trichuriasis Drug: Albendazole|Drug: Levamisole Natural History Museum, United Kingdom|Ministry of Health, Tanzania|University of London Phase 4 2006-06-01 2008-04-15
    NCT02845713 Wuchereria Bancrofti Infection Drug: Ivermectin, Diethylcarbamazine Albendazole (IDA) University Hospitals Cleveland Medical Center|Washington University School of Medicine Phase 1 2016-04-01 2016-10-11
    NCT00375583 Lymphatic Filariasis|Wuchereria Bancrofti Infection Drug: DEC/Albendazole National Institute of Allergy and Infectious Diseases (NIAID)|Tuberculosis Research Centre, India|National Institutes of Health Clinical Center (CC) Phase 2 2006-09-09 2017-01-24
    NCT01395381 Kwashiorkor|Marasmus Drug: Placebo|Drug: Albendazole Washington University School of Medicine|University of Malawi College of Medicine 2013-01-01 2014-01-24
    NCT00130910 HIV Infections|Helminthiasis Drug: Albendazole|Drug: Placebo University of Washington|Kenya Medical Research Institute|University of Nairobi|Kenyatta National Hospital 2006-03-01 2007-11-13
    NCT00207753 Ascariasis|Trichuriasis|Hookworm Infection|Strongyloidiasis|Pediculosis Drug: albendazole vs. combined albendazole/ivermectin treatment Centers for Disease Control and Prevention|Universidad del Valle, Guatemala 2005-02-01 2005-11-16
    NCT01903057 Trachoma|Lymphatic Filariasis Drug: azithromycin|Drug: ivermectin|Drug: albendazole|Drug: placebo Emory University Phase 4 2014-02-01 2014-05-21
    NCT00339417 Lymphatic Filariasis Drug: Albendazole|Drug: Ivermectin National Institute of Allergy and Infectious Diseases (NIAID)|National Institutes of Health Clinical Center (CC) Phase 2 2006-02-22 2017-01-24
    NCT03032042 Helminth Infection Drug: Azithromycin|Drug: Albendazole|Drug: Delayed treatment Francis I. Proctor Foundation Phase 4 2017-01-01 2017-01-23

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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