Home > P2Y Receptor & P2Y Receptor & > Clopidogrel

Clopidogrel

氯吡格雷,氯匹多瑞,SR 25990C,SR25990C,SR-25990C,(S)-(+)-Clopidogrel bisulfate,Plavix,(S)-(+)-Clopidogrel hydrogen sulfate

S-(+)-Clopidogrel hydrogen sulfate是clopidogrel的S型对映异构体，是P2Y12受体抑制剂。

目录号
EY1316
EY1316
纯度
99.19%
99.19%
规格
100 mg
500 mg
原价
460
1100
售价
460
1100
库存
现货
现货
订购
订购
订购
订购
订购
订购
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  • 生物活性

    Clopidogrel is an oral, thienopyridine class antiplatelet agent.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Laine L, et al. Am J Gastroenterol, 2010, 105(1), 34-41.

    分子式
    C16H18ClNO6S2    		 分子量
    419.9    		 CAS号
    120202-66-6    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    80 mg/mL    		 Water
    75 mg/mL    		 Ethanol
    40 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01341600 Metabolism of Clopidogrel Drug: Clopidogrel, Omeprazole University of Maryland|Food and Drug Administration (FDA)|National Cancer Institute (NCI)|National Institute of General Medical Sciences (NIGMS) 2010-07-01 2012-09-28
    NCT01503658 Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel|Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel Drug: Clopidogrel+Aspirin Seoul National University Hospital Phase 4 2012-01-01 2012-06-18
    NCT02185534 Bioequivalence, AUC, Cmax, Pharmacokinetics Drug: Clopidogrel AstraZeneca Phase 1 2014-08-01 2016-05-18
    NCT02048228 CLOPIDOGREL, POOR METABOLISM of (Disorder) Drug: genotyping guided therapy Ticagrelor, Clopidogrel|Drug: standard therapy clopidogrel Chinese PLA General Hospital Phase 2|Phase 3 2014-10-01 2014-04-10
    NCT01097343 Disease Susceptibility Drug: clopidogrel 75 mg|Drug: Clopidogrel 150 mg University of North Carolina, Chapel Hill Phase 2 2010-03-01 2014-02-26
    NCT01960296 Clopidogrel Drug: Clopidogrel|Drug: Discontinue Clopidogrel Icahn School of Medicine at Mount Sinai|Doris Duke Charitable Foundation Phase 2 2012-01-01 2015-11-04
    NCT02010632 Pharmacodynamics Drug: Generic clopidogrel product Apolets|Drug: Original clopidogrel product Plavix Khon Kaen University Phase 1 2013-08-01 2015-04-16
    NCT01512485 Healthy Drug: Clopidogrel Dr. Reddy's Laboratories Limited Phase 1 2006-10-01 2012-01-13
    NCT01493999 Acute Coronary Syndrome Drug: Clopidogrel reloading|Drug: Prasugrel University of Pecs Phase 4 2011-09-01 2014-10-06
    NCT02628587 Acute Coronary Syndrome Drug: Generic clopidogrel|Drug: Patent clopidogrel Hospital Central San Luis Potosi, Mexico Phase 4 2016-02-01 2015-12-09
    NCT01212302 Coronary Artery Disease Drug: Optimizing ASA and clopidogrel treatment Ruhr University of Bochum 2008-10-01 2011-08-11
    NCT00724880 Coronary Artery Disease Drug: Clopidogrel|Drug: Clopidogrel|Drug: Clopidogrel Catharina Ziekenhuis Eindhoven Phase 4 2006-06-01 2008-07-28
    NCT02411903 Cerebral Infarction|Clopidogrel,Poor Metabolism of (Disorder) Drug: atorvastatin and clopidogrel|Drug: rosuvastatin and clopidogrel The Third Affiliated Hospital of Guangzhou Medical University Phase 4 2015-03-01 2015-06-14
    NCT01094275 Coronary Artery Disease Drug: Clopidogrel 75mg, Omeprazole 20mg Neil Kleiman, MD|The Methodist Hospital System Phase 4 2010-01-01 2016-03-15
    NCT00799045 Migraine Drug: Clopidogrel Laval University|Sanofi|Bristol-Myers Squibb Phase 4 2008-10-01 2015-05-11
    NCT01447563 Comparative Bioavailability of Clopidogrel Tablets Drug: Clopidogrel bisulfate|Drug: Clopidogrel Hospital Universitario Dr. Jose E. Gonzalez Phase 1 2008-05-01 2011-10-05
    NCT02054663 Acute Coronary Syndrome Drug: Clopidogrel Ottawa Heart Institute Research Corporation Phase 4 2013-12-01 2015-03-28
    NCT02938182 Migraine Drug: clopidogrel First Affiliated Hospital Xi'an Jiaotong University Phase 4 2016-10-01 2016-10-17
    NCT01506713 Fasting Drug: Clopidogrel Dr. Reddy's Laboratories Limited Phase 1 2006-09-01 2012-01-09
    NCT03039205 Platelet Aggregation|Adenosine|Coronary Artery Disease|Kidney Dysfunction|Antiplatelet Therapy Drug: Clopidogrel|Drug: Ticagrelor University of Sao Paulo|Fundao de Amparo Pesquisa do Estado de So Paulo Phase 2 2017-02-15 2017-01-30
    NCT01621763 Healthy Drug: Clopidogrel Dr. Reddy's Laboratories Limited Phase 1 2008-09-01 2012-06-22
    NCT01129063 Healthy Drug: Clopidogrel Sanofi|Bristol-Myers Squibb Phase 1 2009-03-01 2010-08-27
    NCT01621750 Fasting Drug: Clopidogrel Dr. Reddy's Laboratories Limited Phase 1 2008-08-01 2012-06-14
    NCT01706510 Coronary Artery Disease Drug: Ticagrelor|Drug: Clopidogrel Rapid City Regional Hospital, Inc|AstraZeneca Phase 4 2012-12-01 2015-05-04

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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