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Omeprazole

奥美拉唑,艾美拉唑

Omeprazole (奥美拉唑; Prilosec) 是质子泵抑制剂，可作用于消化不良。

目录号
EY1309
EY1309
EY1309
纯度
99.59%
99.59%
99.59%
规格
25 mg
50 mg
100 mg
原价
360.00
435.00
750.00
售价
360.00
435.00
750.00
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
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  • 生物活性

    Omeprazole is a proton pump inhibitor, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Dzeletovic N, et al. J Biol Chem, 1997, 272(19), 12705-12713.

    分子式
    C17H19N3O3S    		 分子量
    345.42    		 CAS号
    73590-58-6    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    50 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    4 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01657578 Gastroesophageal Reflux Disease (GERD) Drug: Omeprazole Assistance Publique - Hpitaux de Paris Phase 2 2007-06-01 2012-10-10
    NCT01921920 Bioequivalence, AUC, Cmax, Pharmacokinetics Drug: Omeprazole AstraZeneca Phase 1 2013-08-01 2013-11-21
    NCT01045434 Healthy Drug: Omeprazole Dr. Reddy's Laboratories Limited Phase 1 2006-12-01 2010-01-19
    NCT00861640 Nonvariceal Upper Gastrointestinal Bleeding Drug: Intravenous Omeprazole|Drug: Oral Rabeprazole Kaohsiung Medical University Chung-Ho Memorial Hospital|Kaohsiung Medical University Phase 4 2009-03-01 2009-07-14
    NCT01711320 Healthy Drug: Placebo|Drug: Omeprazole Xijing Hospital Phase 1 2012-09-01 2013-03-16
    NCT01170182 Healthy Drug: Omeprazole|Device: Prilosec 40 mg Dr. Reddy's Laboratories Limited Phase 1 2006-02-01 2010-07-26
    NCT02085018 Idiopathic Pulmonary Fibrosis Drug: Omeprazole|Drug: Matched placebo Newcastle-upon-Tyne Hospitals NHS Trust|Newcastle University Phase 2 2014-02-01 2015-10-08
    NCT01045642 Healthy Drug: Omeprazole Dr. Reddy's Laboratories Limited Phase 1 2006-12-01 2010-01-19
    NCT00693225 Erosive Esophagitis Drug: Omeprazole/sodium bicarbonate Yvonne Romero|Valeant Pharmaceuticals International, Inc.|Mayo Clinic Phase 4 2008-01-01 2012-08-21
    NCT01337804 Heartburn Drug: omeprazole/sodium bicarbonate|Drug: omeprazole magnesium Bayer Phase 1 2011-01-01 2015-02-20
    NCT00272467 Stomach Ulcer Drug: Rebamipide|Drug: Omeprazole Korea Otsuka International Asia Arab|Zhejiang Otsuka Pharmaceutical Co., Ltd.|Korea Otsuka Pharmaceutical Co., Ltd. Phase 4 2005-07-01 2015-04-27
    NCT01587885 Heartburn Drug: Omeprazole 20 mg + Sodium Bicarbonate 1100 mg|Drug: Omeprazole 20 mg Bayer Phase 4 2012-01-01 2015-02-20
    NCT02536989 Peptic Ulcer|Hemorrhage Drug: omeprazole|Drug: omeprazole Far Eastern Memorial Hospital Phase 4 2009-03-01 2016-02-05
    NCT00537732 Gastroesophageal Reflux Drug: omeprazole|Drug: omeprazole Matthias Schwab|Robert Bosch Gesellschaft fr Medizinische Forschung mbH Phase 4 2007-04-01 2014-02-24
    NCT01094275 Coronary Artery Disease Drug: Clopidogrel 75mg, Omeprazole 20mg Neil Kleiman, MD|The Methodist Hospital System Phase 4 2010-01-01 2016-03-15
    NCT00582972 Osteoporosis|Achlorhydria|GERD|Hip Fracture Drug: Omeprazole University of Wisconsin, Madison Phase 4 2008-01-01 2013-02-14
    NCT02140073 GERD Drug: omeprazole+domperidone SR|Drug: omeprazole Belarusian Medical Academy of Post-Graduate Education|Dr. Reddy's Laboratories Limited Phase 4 2013-12-01 2014-05-15
    NCT02730026 Pain|Other Surgical Procedures Drug: Ketoprofen|Drug: Ketoprofen and Omeprazole Luis Fernando Simoneti|Fundao de Amparo  esquisa do Estado de So Paulo|University of Sao Paulo Phase 4 2015-06-01 2017-03-08
    NCT01170169 Healthy Drug: Omeprazole|Drug: Prilosec Dr. Reddy's Laboratories Limited Phase 1 2006-01-01 2010-07-26
    NCT01470690 HCV Infections|Gastric Acid-related Disorders Drug: boceprevir|Drug: Omeprazole Radboud University|Merck Sharp & Dohme Corp. Phase 1 2011-10-01 2012-11-26
    NCT00256737 GERD Drug: Omeprazole AstraZeneca Phase 3 1998-01-01 2011-01-21
    NCT02922933 Volunteers|Healthy Volunteers|Human Volunteers|Normal Volunteers Drug: entinostat|Dietary Supplement: Omeprazole|Dietary Supplement: Famotidine Syndax Pharmaceuticals Phase 1 2016-11-01 2017-01-30
    NCT02190708 Healthy Volunteers|Pharmacologic Action Drug: PQ912|Drug: Midazolam|Drug: Omeprazole Probiodrug AG|Covance Phase 1 2014-06-01 2015-10-19
    NCT01735227 Acute Coronary Syndromes Drug: omeprazole|Drug: Pantoprazole Yaling Han|Shenyang Northern Hospital Phase 4 2012-11-01 2012-11-27
    NCT00971581 Pain Drug: FDC KETOPROFEN+OMEPRAZOLE Sanofi Phase 3 2009-08-01 2010-06-28

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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