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Moxifloxacin HCl

盐酸莫西沙星,BAY12-8039 HCl

Moxifloxacin Hydrochloride是一种第四代氟喹诺酮类抗生素。

目录号
EY1280
EY1280
EY1280
纯度
99.27%
99.27%
99.27%
规格
50 mg
100 mg
500 mg
原价
610
940
2300
售价
610
940
2300
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Tuberculosis (Edinb), 2008, 88(2):127-131.

    分子式
    C21H24FN3O4.HCl
    分子量
    437.89
    CAS号
    186826-86-8
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    88 mg/mL
    Water
    24 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02016157 Chronic Generalized Periodontitis Drug: Moxifloxacin Sri Hasanamba Dental College and Hospital Phase 4 2011-09-01 2013-12-18
    NCT01302951 Side-effect of Antibiotic Drug: Moxifloxacin 400 mg University Hospital, Saarland|Bayer Phase 4 2008-07-01 2011-02-23
    NCT02595359 Endophthalmitis Drug: Moxifloxacin Universidade Federal de Pernambuco Phase 2 2013-01-01 2016-10-24
    NCT02770729 Endophthalmitis Drug: Moxifloxacin|Drug: No injection of moxifloxacin University of Campinas, Brazil Phase 3 2017-01-01 2017-03-15
    NCT01756521 the Effect of Moxifloxacin on QT/QTc Interval Drug: Moxifloxacin Seoul National University Hospital|Korea National Enterprise for Clinical Trials|The Catholic University of Korea|Seoul National University Bundang Hospital Phase 1 2013-01-01 2016-04-25
    NCT01876316 Healthy Drug: Moxifloxacin|Drug: Placebo Inje University 2011-11-01 2013-06-11
    NCT00895089 Liver Abscess Drug: Moxifloxacin (Avelox)|Drug: ceftriaxone Kaohsiung Veterans General Hospital.|Bayer Phase 4 2009-05-01 2015-12-01
    NCT02322619 Healthy Drug: Moxifloxacin Tablets 400 mg Dr. Reddy's Laboratories Limited Phase 1 2012-11-01 2014-12-18
    NCT01055145 TB Drug: levofloxacin, moxifloxacin Seoul National University Hospital Phase 3 2010-03-01 2012-11-22
    NCT01603030 Eye Infection/Inflammation Other Drug: moxifloxacin 0,5% + prednisolone 1%|Drug: moxifloxacin/prednisolone combination Adapt Produtos Oftalmolgicos Ltda. Phase 3 2012-06-01 2012-05-21
    NCT01130922 Gastric Bypass|Body Weight Drug: moxifloxacin per IV|Drug: moxifloxacin per os University Ghent Phase 4 2010-03-01 2011-04-15
    NCT02176005 Healthy Device: DAV132|Drug: Moxifloxacin|Other: Negative Control Da Volterra Phase 1 2014-03-01 2016-02-03
    NCT01642485 Effects of Different Meals on the QT/QTc Interval|Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use|C-Peptide Effects on the QT/QTc Interval|Moxifloxacin ECG Profile in Fed and Fasted State|Japanese vs. Caucasian TQT Comparison Drug: Moxifloxacin 400 mg fasted|Other: FDA breakfast|Other: Continental breakfast|Drug: Moxifloxacin 400 mg fed|Procedure: Insulin Clamp|Drug: Placebo Richmond Pharmacology Limited Phase 1 2011-07-01 2014-08-19
    NCT02531438 Bacterial Pneumonia|Community-Acquired Infections Drug: Omadacycline|Drug: Moxifloxacin Paratek Pharmaceuticals Inc Phase 3 2015-11-01 2017-01-24
    NCT00805558 Chronic Periodontitis Drug: moxifloxacin|Drug: Ciprofloxacin plus metronidazole Facultad Nacional de Salud Publica|Universidad de Antioquia Phase 4 2009-02-01 2010-05-10
    NCT00764582 Corneal Transplantation Drug: 1.5% levofloxacin ophthalmic solution|Drug: 0.5% moxifloxacin ophthalmic solution Santen Inc.|Vistakon Pharmaceuticals Phase 4 2008-09-01 2009-08-24
    NCT01653990 QT Interval Prolongation Drug: moxifloxacin|Drug: moxifloxacin-placebo Peking University Third Hospital 2012-07-01 2012-07-30
    NCT00728507 Tuberculosis Drug: Rifapentine, Moxifloxacin, Pyrazinamide, Isoniazid|Drug: Isoniazid, Rifampin, Pyrazinamide, Ethambutol Johns Hopkins University|Universidade Federal do Rio de Janeiro|Municipal Health Secretary of Rio de Janeiro|Helio Fraga Reference Center, Fiocruz Phase 2 2009-11-01 2013-04-01
    NCT01191723 Healthy Drug: MAP0004|Drug: Inhaler Placebo|Drug: Moxifloxacin|Drug: Placebo Capsule Allergan|MAP Pharmaceuticals, Inc., a wholly owned subsidiary of Allergan Phase 1 2010-08-01 2013-12-09
    NCT00887276 Community Acquired Pneumonia Drug: Moxifloxacin|Drug: Ampicillin;Amoxicillin University of Ulm|CAPNETZ Stiftung Phase 4 2008-11-01 2014-12-16
    NCT00398411 Hodgkin Disease|Non-Hodgkin Lymphoma|Multiple Myeloma|Bacteremia Drug: moxifloxacin|Drug: placebo University of Cologne Phase 3 2006-10-01 2015-06-01
    NCT00840580 Cataract Extraction Drug: Moxifloxacin 0.5% ophthalmic solution (Vigamox)|Drug: Levofloxacin 0.5% ophthalmic solution (Cravit) Alcon Research Phase 4 2009-01-01 2012-07-19

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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