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Gentamicin Sulfate

硫酸庆大霉素,NSC-82261,SCH9724,NSC82261,NSC 82261,SCH 9724,SCH-9724,

Gentamicin Sulfate是一种广谱的氨基糖苷类抗生素,用于细胞培养,抑制敏感机体的蛋白合成。

目录号
EY1250
EY1250
纯度
99.64%
99.64%
规格
500 mg
1 g
原价
520
720
售价
520
720
库存
现货
现货
订购
订购
订购
订购
订购
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  • 生物活性

    Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Martin NL, et al. Antimicrob Agents Chemother. 1986 Jun;29(6):1079-87.

    分子式
    C21H43N5O7.H2SO4
    分子量
    575.67
    CAS号
    1405-41-0
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    <1 mg/mL
    Water
    100 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01287780 Surgical Wound Infection Device: Collagen-gentamicin sponge Oslo University Hospital Phase 3 2011-01-01 2013-08-15
    NCT01884467 Urinary Tract Infections Drug: Gentamicin|Drug: Placebo Gillette Children's Specialty Healthcare Phase 4 2013-05-01 2015-04-08
    NCT02379754 Vestibular Schwannoma Drug: Gentamicins Lund University Phase 4 2015-01-01 2016-09-06
    NCT00751374 Rate of Exit Site Infection|Rate of Atypical Mycobacterial Infection|Rate of Peritoneal Dialysis Drug: gentamicin|Drug: gentamicin cream alternating with mupirocin cream Kwong Wah Hospital|The Hong Kong Society of Nephrology Phase 4 2008-09-01 2008-09-10
    NCT00451074 Duchenne Muscular Dystrophy Drug: Gentamicin infusions twice a week for six months Nationwide Children's Hospital|National Institutes of Health (NIH)|National Institute of Neurological Disorders and Stroke (NINDS) Phase 1 2007-03-01 2012-03-22
    NCT02427932 Drug Metabolism During Pregnancy Drug: Ampicillin|Drug: Ampicillin and Gentamicin|Drug: Gentamicin Stanford University|David Drover, MD Phase 4 2015-05-01 2015-11-10
    NCT01148693 Cholangitis Drug: gentamicin|Drug: Placebo Tehran University of Medical Sciences 2009-12-01 2011-09-18
    NCT02479971 Pain Drug: Clindamycin-gentamicin irrigation|Drug: Normal saline irrigation Hospital General Universitario Elche Phase 3 2014-01-01 2015-06-22
    NCT00185991 Chorioamnionitis Drug: gentamicin Stanford University 2004-06-01 2011-06-13
    NCT02415257 Vestibular Schwannoma Drug: Gentamicin Lund University Phase 4 2015-04-01 2016-09-06
    NCT00977405 Superficial Surgical Site Infection Device: Collatamp Gentamicin Implant Singapore General Hospital|Novem Healthcare Pte Ltd Phase 2 2009-09-01 2009-09-14
    NCT02582099 Rhinosinusitis Drug: Gentamicin nasal irrigation|Drug: Normal saline nasal irrigation Mahidol University Phase 4 2013-12-01 2016-05-02
    NCT03012191 Recessive Dystrophic Epidermolysis Bullosa Drug: Gentamicin Sulfate University of Southern California Phase 1|Phase 2 2017-01-01 2017-01-05
    NCT01244256 Folliculitis Drug: Clotrimazole + Gentamicin + Beclomethasone|Drug: Clotrimazole + Gentamicin Azidus Brasil Phase 2|Phase 3 2007-04-01 2010-11-18
    NCT01951768 Diabetic Foot Ulcer Drug: Garamycin Sponge (Gentamicin-Collagen sponge)|Drug: Systemic Antibiotic University Hospital, Geneva Phase 4 2013-09-01 2013-09-30
    NCT02898961 Sepsis Drug: 30 mg/kg amikacin or 8 mg/kg gentamicin Centre Hospitalier Universitaire de Nmes Phase 4 2014-10-01 2017-02-02
    NCT02447172 Foot Ulcer, Diabetic|Infection Drug: Gentamicin Collagen sponge|Other: Placebo Innocoll Phase 3 2015-06-01 2016-06-07
    NCT02427802 Foot Ulcer, Diabetic|Infection Drug: Gentamicin collagen sponge|Other: Placebo Innocoll Phase 3 2015-05-01 2016-06-07
    NCT01700504 Axillary Drainage Volume After Lymph Node Dissection. Drug: Axillary lavage with gentamicin solution Hospital General Universitario Elche Phase 3 2011-05-01 2012-10-02
    NCT02314806 Breast Cancer Drug: Irrigation with gentamicin solution|Drug: Irrigation with Clindamycin solution|Drug: Irrigation with Normal saline Hospital General Universitario Elche Phase 3 2013-01-01 2014-12-09

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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