Home > nAChR & mAChR & mAChR & > Acetylcholine Chloride

Acetylcholine Chloride

乙酰胆碱

化合物Acetylcholine Chloride是一种神经递质,作用于包括人类在内的许多生物的周围神经系统(PNS)和中枢神经系统(CNS)。

目录号
EY1149
EY1149
EY1149
纯度
99.79%
99.79%
99.79%
规格
100 mg
500 mg
1 g
原价
330
450
570
售价
330
450
570
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    The chemical compound Acetylcholine Chloride is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Pepeu, G. and Blandina, P. 1998. J. Physiol. Paris. 92: 351-355. PMID: 9789836
    [2] Perry, E., et al. 1999. Trends Neurosci. 22: 273-280. PMID: 10354606
    [3] Lei, X., et al. 2008. Arch. Dermatol. Res. 300: 335-341. PMID: 18386025

    分子式
    C7H16NO2.Cl
    分子量
    181.66
    CAS号
    60-31-1
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    30 mg/mL
    Water
    <1 mg/mL
    Ethanol
    30 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01137656 Healthy Drug: Acetylcholine and Blood Mark Gladwin|National Heart, Lung, and Blood Institute (NHLBI)|University of Pittsburgh Phase 1 2010-04-01 2015-04-10
    NCT01098383 Autism Drug: Acetyl-Choline Esterase Inhibitors and Choline supplements|Drug: Indistinguishable placebo tablets, matching both donepezil and choline Sheba Medical Center|The Israeli Society of Clinical Pediatrics (HIPAK) Phase 4 2010-03-01 2016-10-13
    NCT00350532 Pain Drug: clonidine|Drug: clonidine Wake Forest University Health Sciences|National Institute of Neurological Disorders and Stroke (NINDS) Phase 2 2004-09-01 2014-03-05
    NCT02063542 Necrosis of Femoral Head|Knee Osteoarthritis|Fracture of Lower Limb RenJi Hospital 2014-04-01 2014-05-27
    NCT01242306 Endothelial Dysfunction Drug: intracoronary infusion of acetylcholine Azienda Ospedaliera San Camillo Forlanini Phase 1|Phase 2 2009-03-01 2010-11-16
    NCT01894646 Measure of Uptake of XTRA in the Brain. Radiation: Positron Emission Tomagraphy (PET) Imaging Johns Hopkins University|National Institutes of Health (NIH) 2013-02-01 2015-03-30
    NCT00921856 Coronary Vasospasm|Microvascular Angina|Coronary Artery Disease Other: Intracoronary acetylcholine provocation test Peter Ong, MD|Robert Bosch Medical Center 2007-11-01 2015-11-02
    NCT02008292 Smoking|Schizophrenia Drug: Physostigmine Yale University|National Institutes of Health (NIH)|National Institute on Drug Abuse (NIDA) 2013-09-01 2016-12-15
    NCT02645461 Amyotrophic Lateral Sclerosis Drug: endocannabinoid palmitoylethanolamide (PEA)|Drug: Riluzole University of Roma La Sapienza 2014-01-01 2016-01-01
    NCT01046513 Healthy Volunteers|Nicotine Dependence|Pharmacokinetics National Institute on Drug Abuse (NIDA)|National Institutes of Health Clinical Center (CC) 2007-08-31 2017-01-24
    NCT00987220 Alzheimer's Disease|Dementia Drug: Placebo|Drug: donepezil (Aricept) Pfizer 2009-10-01 2011-02-10
    NCT01848301 Cardiac Allograft Vasculopathy|Antibody Mediated Rejection Device: Optical Coherence Tomography|Drug: Acetylcholine|Procedure: Brachial Artery Flow Mediated Dilation University of Pittsburgh Phase 1 2012-09-01 2016-01-08
    NCT01162824 Endothelial Dysfunction|Atherosclerosis|Inflammation|Myocardial Ischemia Drug: Acetylcholine|Drug: Adenosine St George's Healthcare NHS Trust 2011-01-01 2011-02-22
    NCT02085317 Lepromatous Leprosy Drug: acetylcholine Iontophoresis|Drug: sodium nitroprusside Iontophoresis Curt Treu|Rio de Janeiro State University 2006-03-01 2014-03-10
    NCT00259701 Diabetes|Retinopathy|Vascular Pathology Device: Laser Doppler Flowmetry with topical acetylcholine and nitroglycerin Yale University 2005-06-01 2006-10-05
    NCT00061789 Schizophrenia Drug: SPECT Imaging of Nicotinic Acetylcholine Receptors in Brain National Institute of Mental Health (NIMH)|National Institutes of Health Clinical Center (CC) Phase 2 2003-02-01 2008-03-03
    NCT00917709 Dementia With Lewy Bodies Other: Imaging with IBVM|Other: Imaging with DATSCAN|Behavioral: neuropsychological evaluation University Hospital, Bordeaux 2009-05-01 2014-08-20
    NCT02138708 Pulmonary Arterial Hypertension With Congenital Cardiac Shunt Other: Pharmacological test of pulmonary endothelial Assistance Publique - H么pitaux de Paris 2016-01-01 2015-07-20
    NCT00184847 Ischemia-Reperfusion Injury Drug: acetylcholine|Procedure: twenty minutes of forearm ischemia|Procedure: three 5-minute periods of forearm ischemia|Drug: adenosine|Drug: caffeine Radboud University 2005-03-01 2008-03-27
    NCT02034331 Spinal Cord Injury|Insulin Resistance Drug: Insulin iontophoresis|Drug: Placebo Iontophoresis|Drug: Acetylcholine Iontophoresis|Other: Heat application James J. Peters Veterans Affairs Medical Center 2012-12-01 2017-03-06

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 :
  • 收件地址 :
  • 电话号码 :
  • 单位名称 :
  • 产品货号 :
  • 产品规格 :
  • 发票抬头以及单位税号 :