Tolnaftate是合成的硫代氨基甲酸酯类抗真菌化合物。
Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] J Pannu et. Al. Antimicrobial Agents and Chemotherapy, 53(8), 3273-3279 (2009).
[2] H Vanden Bossche et. Al. Journal of Veterinary Pharmacology and Therapeutics, 26(1), 5-29 (2003).
分子式 C19H17NOS |
分子量 307.41 |
CAS号 2398-96-1 |
储存方式 ﹣20 ℃冷藏长期储存。冰袋运输 |
溶剂(常温) |
DMSO 62 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
NCT Number | Conditions | Interventions | Sponsor/Collaborators | Phases | Start Date | Last Updated |
NCT01105013 | Fungal Infections|Tinea Pedis|Tinea Cruris|Tinea Corporis | Drug: Clotrimazole | Laboratrio Teuto Brasileiro S/A | Phase 3 | 2012-04-01 | 2012-04-11 |
NCT02600936 | Peripheral Venous Outflow Obstruction | Device: vein stent placement | Windsor Ting|Boston Scientific Corporation|Icahn School of Medicine at Mount Sinai | 2017-06-01 | 2016-12-13 | |
NCT01429701 | Eczema | Drug: polymyxin B sulphate + prednisolone + benzocaine + clioquinol|Drug: betamethasone + gentamicin + tolnaftato + cleoquinol | EMS | Phase 3 | 2012-05-01 | 2013-03-01 |
NCT02169258 | Peripheral Artery Disease|Coronary Artery Disease | Procedure: Systemic Strategy | National Cheng-Kung University Hospital|Tainan Municipal Hospital|E-DA Hospital|Kaohsiung Medical University|National Taiwan University Hospital|Buddhist Tzu Chi General Hospital|Far Eastern Memorial Hospital|University of Alberta | 2014-06-01 | 2015-09-23 | |
NCT02084277 | Malocclusion | Device: Self-ligating brackets (SLB)|Device: Conventional brackets (CB) | Mackay Memorial Hospital | 2010-06-01 | 2014-03-09 | |
NCT01281683 | Hepatocellular Carcinoma | National Taiwan University Hospital | 2011-01-01 | 2011-01-20 | ||
NCT01412476 | Metabolic Syndrome | Chung Shan Medical University|National Science Council, Taiwan | 2010-08-01 | 2012-03-23 | ||
NCT01273701 | Amphetamine Abuse|Amphetamine Dependence|Methamphetamine Abuse|Methamphetamine Dependence | Behavioral: Psychosocial intervention|Behavioral: Telephone reminding | National Taiwan University Hospital | 2011-01-01 | 2011-01-06 | |
NCT02574065 | Crying Time in Colicky Infants | Drug: L. reuteri DSM 17938|Other: The placebo consists of an identical formulation without L. reuteri DSM 17938 | Shanghai Children's Hospital|BioGaia AB|Suzhou University Affiliated Children's Hospital|Shanghai Children's Medical Center | 2016-03-01 | 2016-10-27 | |
NCT01974505 | Intubation, Intratracheal | Device: intubation using optiscope | Jeju National University School of Medicine | 2013-11-01 | 2013-10-28 | |
NCT00695110 | Hypogonadism | Drug: Testosterone undecanoate (TU)|Drug: TU + testosterone enanthate (TE)|Drug: Testosterone undecanoate (TU)|Drug: TU + testosterone enanthate (TE) | Clarus Therapeutics, Inc.|Los Angeles Biomedical Research Institute | Phase 2 | 2008-06-01 | 2010-08-23 |
NCT02995707 | Thalassemia | Drug: Thalidomide | Xiao-Lin Yin|303rd Hospital of the People's Liberation Army | Phase 2 | 2016-09-01 | 2017-03-21 |
NCT03090516 | Alzheimer's | Drug: Ginkgo biloba dispersible tablets|Drug: Donepezil|Drug: Ginkgo biloba dispersible tablets and Donepezil | The First Affiliated Hospital with Nanjing Medical University | Phase 2|Phase 3 | 2016-08-10 | 2017-03-23 |
NCT02815163 | Empowerment | Other: Empowerment education | Tzu-Ting Huang|Chang Gung Memorial Hospital | 2013-09-01 | 2016-06-27 | |
NCT00314301 | Cerebral Palsy | Device: loaded sit-to-stand training | Far Eastern Memorial Hospital|National Taiwan University | 2006-04-01 | 2006-04-14 | |
NCT00172562 | Acute Myeloid Leukemia | National Taiwan University Hospital | Phase 3 | | 2006-02-28 | |
NCT00172315 | Acquired Immunodeficiency Syndrome|Lipodystrophy | National Taiwan University Hospital | Phase 3 | 2003-12-01 | 2006-03-28 | |
NCT01937429 | Adenoma Detection to Prevent Colorectal Cancer | Device: Colonoscopy with blue Indigo Carmin|Device: Standard colonoscopy with insufflation of air | Hospices Civils de Lyon | Phase 3 | 2013-01-01 | 2013-09-06 |
NCT00924612 | Male Hypogonadism | Drug: Oral testosterone undecanoate (containing 300 mg of T) | Clarus Therapeutics, Inc. | Phase 2 | 2009-07-01 | 2010-08-23 |
NCT00911586 | Male Hypogonadism|Primary Hypogonadism|Secondary Hypogonadism | Drug: Testosterone undecanoate | Clarus Therapeutics, Inc. | Phase 2 | 2009-07-01 | 2010-08-17 |
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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