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Pitavastatin Calcium

匹伐他汀钙,NK-104 Calcium,NK104 Calcium,NK 104 Calcium

Pitavastatin是HMG-CoA还原酶的竞争性抑制剂。

目录号
EY1114
EY1114
EY1114
EY1114
纯度
99.51%
99.51%
99.51%
99.51%
规格
1 mg
5 mg
10 mg
100 mg
原价
120
300
482
1800
售价
120
300
482
1800
库存
现货
现货
现货
现货
订购
订购
订购
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  • 生物活性

    Pitavastatin calcium is a novel member of the medication class of statins.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Ahmad H, et al. Cardiol Rev, 2010, 18(5):264-267.

    分子式
    C50H46CaF2N2O8    		 分子量
    880.98    		 CAS号
    147526-32-7    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    50 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02056847 HbA1c Level Associated With Lipid Compositions Drug: Pitavastatin calcium 4mg|Drug: Pitavastatin calcium 2mg JW Pharmaceutical|The Catholic University of Korea|Kyunghee University Medical Center|Korea University Guro Hospital|Dong-A University Hospital|Seoul National University Bundang Hospital|Samsung Medical Center|Seoul National University Hospital|Ajou University School of Medicine|Gangnam Severance Hospital|Severance Hospital|Yeungnam University|Ulsan University Hospital|Eulji University Hospital|Asan Medical Center|Chonnam National University Hospital|Chonbuk National University Hospital|Chungnam National University Hospital|Hallym University Medical Center Phase 4 2014-01-01 2017-03-08
    NCT00344370 Type II Diabetes Mellitus|Dyslipidemia Drug: Pitavastatin|Drug: Atorvastatin Kowa Research Europe Phase 3 2006-08-01 2010-01-25
    NCT00309751 Type II Diabetes Mellitus|Dyslipidemia Drug: Pitavastatin|Drug: Atorvastatin Kowa Research Europe Phase 3 2005-12-01 2010-02-17
    NCT00889226 Hypercholesterolemia With Type2DM Drug: Pitavastatin|Drug: Atorvastatin JW Pharmaceutical Phase 4 2008-04-01 2013-04-02
    NCT01386853 Hyperlipidemia Drug: Pitavastatin|Drug: Atorvastatin Tai Tien Pharmaceuticals Co., Ltd. Phase 3 2011-07-01 2011-06-30
    NCT01648829 Coronary Artery Disease Drug: Atorvastatin|Drug: Pitavastatin University of Roma La Sapienza Phase 4 2014-01-01 2013-03-06
    NCT02863185 Chronic Kidney Disease Drug: Pitavastatin|Drug: Atorvastatin Dong-A University Phase 4 2016-05-01 2016-08-14
    NCT02940366 Metabolic Syndrome Drug: Pitavastatin 4 mg orally daily|Drug: Atorvastatin 20 mg orally daily Seoul National University Hospital|JW Pharmaceutical Phase 4 2016-12-01 2017-02-08
    NCT00861861 Hypercholesterolemia|Coronary Artery Disease Drug: Pitavastatin|Drug: Atorvastatin Kumamoto University Phase 4 2008-09-01 2013-10-11
    NCT00249249 Primary Hypercholesterolemia|Dyslipidemia Drug: Pitavastatin|Drug: Atorvastatin Kowa Research Europe Phase 3 2005-10-01 2010-01-07
    NCT01223586 Statin|Coronary Plaque|Acute Coronary Syndrome|Intravascular Ultrasound|Cardiovascular Events Kyoto University|Yamaguchi University Hospital 2010-11-01 2012-04-21
    NCT01710007 Hypercholesterolemia Drug: 1PC002|Drug: Lipitor Orient Pharma Co., Ltd.|Orient Europharma Co., Ltd. Phase 3 2011-11-01 2013-06-14
    NCT01660191 Hypercholesterolemia Drug: Pitavastin 4mg|Drug: Atorvastatin 20mg|Drug: Rosuvastatin 5mg University of Kansas Medical Center|Kowa Pharmaceuticals America, Inc.|Eli Lilly and Company Phase 4 2011-12-01 2016-11-22
    NCT00242944 Coronary Disease|Hypercholesterolemia Drug: Pitavastatin|Drug: Atorvastatin Kyoto University|Yamaguchi University Hospital|Juntendo University School of Medicine Phase 4 2005-11-01 2009-12-16
    NCT01166633 Hypercholesterolemia Drug: pitavastatin|Drug: atorvastatin JW Pharmaceutical Phase 4 2009-06-01 2013-04-02
    NCT01178853 Healthy Drug: Warfarin|Drug: Warfarin 5mg + Rosuvastatin 40 mg once daily (QD)|Drug: Warfarin 5 mg + Pitavastatin 4mg once daily (QD) Kowa Research Institute, Inc. Phase 4 2010-07-01 2012-09-06
    NCT00549926 Coronary Disease|Hypercholesterolemia Drug: Fluvastatin|Drug: Pravastatin|Drug: Pitavastatin|Drug: Atorvastatin Yokohama City University Medical Center Phase 4 2007-10-01 2010-02-16
    NCT00716846 Healthy Volunteers Drug: simvastatin|Drug: atorvastatin|Drug: pitavastatin Hamamatsu University 2006-06-01 2011-09-05
    NCT01422382 Healthy Drug: Pitavastatin (NK-104)|Drug: Diltiazem (Cardizem LA) 240 mg QD Kowa Research Institute, Inc. Phase 4 2011-05-01 2012-07-05

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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