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Haloperidol

氟哌丁苯,氟哌啶醇 Haloperidol hydrochloride Haloperidol lactate

Haloperidol 是一种丁酰苯类的抗精神病药。

目录号
EY1048
EY1048
纯度
99.27%
99.27%
规格
100 mg
500 mg
原价
420
710
售价
420
710
库存
现货
现货
订购
订购
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  • 生物活性

    Haloperidol (Haldol) is an antipsychotic and butyrophenone.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Ashish K Mishra et. Al. Biochemical Journal, 466(2), 263-271 (2015).
    [2] A G Pinder et. Al. British journal of pharmacology and chemotherapy, 157(8), 1523-1530 (2009).
    [3] T Nakahara et. Al. Molecular Brain Research, 73(1-2), 193-197 (1999).

    分子式
    C21H23ClFNO2    		 分子量
    375.86    		 CAS号
    52-86-8    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    73 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    5 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01862302 Postoperative Confusion Drug: Haloperidol|Drug: Placebo McMaster University Phase 3 2013-08-01 2016-09-15
    NCT02057549 Gastroparesis Drug: Haloperidol The University of Texas Health Science Center, Houston Phase 4 2012-11-01 2017-01-30
    NCT01193621 Healthy Drug: haloperidol, PET Asan Medical Center|Seoul National University Hospital Phase 1 2008-01-01 2013-07-10
    NCT01785290 Delirium Drug: Haloperidol 1 mg/q8h|Drug: Haloperidol 2 mg/q8h|Drug: Placebo Radboud University|ZonMw: The Netherlands Organisation for Health Research and Development Phase 4 2013-06-01 2015-12-02
    NCT02103881 Agitation Drug: Ketamine|Drug: Haloperidol Jon B Cole|Minneapolis Medical Research Foundation Phase 4 2014-04-01 2015-09-21
    NCT00169091 Schizophrenia Drug: Clozapine|Drug: Haloperidol Harvard Medical School|National Institute of Mental Health (NIMH)|Dartmouth-Hitchcock Medical Center|Commonwealth Research Center, Massachusetts|Novartis Phase 4 1996-03-01 2015-04-06
    NCT00625014 Insulin Resistance|Dyslipidemia Drug: Haloperidol Leiden University Medical Center|Dutch Diabetes Research Foundation 2005-03-01 2008-02-19
    NCT00947375 Schizophrenia Drug: Lamictal TM|Drug: Haloperidol Decanoate Central Mental Clinic for Outpatients of Baku City Phase 4 2005-01-01 2009-07-27
    NCT01684969 Nausea|Vomiting Drug: Haloperidol|Drug: Placebo Eric E. Prommer|Mayo Clinic Early Phase 1 2012-03-01 2016-03-16
    NCT03021486 Malignant Neoplasms of Independent (Primary) Multiple Sites Drug: Haloperidol|Drug: Chlorpromazine|Behavioral: Symptom Questionnaire M.D. Anderson Cancer Center|National Institutes of Health (NIH) Phase 2|Phase 3 2017-05-01 2017-03-23
    NCT00753051 Schizophrenia Drug: clozapine+haloperidol|Drug: clozapine,electroconvulsive therapy Khon Kaen University 2008-06-01 2012-05-04
    NCT03056482 Cannabis Use Disorder Drug: Ondansetron 8mg|Drug: Haloperidol 0.05mg/kg|Drug: Haloperidol 0.1mg/kg Queen's University Phase 4 2017-04-03 2017-02-14
    NCT01750541 Psychomotor Agitation Drug: Haloperidol|Drug: Valproate Shahid Beheshti University of Medical Sciences Phase 3 2012-12-01 2013-01-05
    NCT00797277 Schizophrenia|Schizoaffective Disorder|Agitation Drug: IM olanzapine|Drug: IM haloperidol plus lorazepam National Taiwan University Hospital|Yu-Li Hospital Phase 3 2006-07-01 2014-09-11
    NCT00954603 Delirium Drug: quetiapine|Drug: haloperidol Chiang Mai University Phase 3 2009-06-01 2011-06-22
    NCT02972502 Headache, Migraine Drug: Metoclopramide|Drug: Haloperidol|Other: Normal Saline|Drug: Diphenhydramine OhioHealth Phase 4 2014-02-01 2016-11-21
    NCT01174290 Subsyndromal Delirium Drug: Haloperidol decanoate|Drug: Placebo Northeastern University|National Institute on Aging (NIA) Phase 4 2010-09-01 2012-04-27
    NCT00833300 Delirium|Agitation Drug: Haloperidol|Drug: Olanzapine Richard Hall|Dalhousie University|Nova Scotia Health Authority 2008-06-01 2012-08-02
    NCT01639599 Gynecological Disease Drug: Dexamethasone iv injection|Drug: Dexamethasone, haloperidol|Drug: Dexamethasone, haloperidol The Catholic University of Korea 2012-03-01 2014-06-12
    NCT00505804 Delirium|Agitation|Ventilator Weaning|Respiration, Artificial|Intensive Care Drug: dexmedetomidine|Drug: haloperidol Austin Health|The Alfred Phase 2 2005-01-01 2013-01-22

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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