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Grape Seed Extract

葡萄籽提取物

Grape Seed Extract 是整个葡萄籽中的工业衍生物，具有很高浓度的维生素E，类黄酮，亚油酸，和OPCs。

目录号
EY1029
EY1029
EY1029
纯度
99.31%
99.31%
99.31%
规格
100 mg
250 mg
500 mg
原价
450
890
1600
售价
450
890
1600
库存
现货
现货
现货
订购
订购
订购
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  • 生物活性

    Grape Seed Extract are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Binit Shrestha,et al. Asian Pac J Trop Biomed. 2012 Oct; 2(10): 822–825. doi: 10.1016/S2221-1691(12)60236-6.

    分子式
    C30H12O6    		 分子量
    468.42    		 CAS号
    84929-27-1    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    >90 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02939417 Retention & Fracture of Emax Laminate Veneers Other: Grape seed extract Marwa Salem|Cairo University 2016-11-01 2016-10-18
    NCT00713167 Hyperlipidemia Drug: Grape Seed Extract (Vitagrape)|Drug: Placebo of Grape Seed Extract Shahid Beheshti University of Medical Sciences|Tabriz University Phase 2|Phase 3 2008-07-01 2009-05-20
    NCT00979732 Hypertension Dietary Supplement: grape seed extract|Dietary Supplement: grape seed extract placebo Institute for Food Safety and Health, United States|Polyphenolics, Inc. 2009-11-01 2017-02-06
    NCT00566553 Breast Cancer Dietary Supplement: Grape Seed Extract|Dietary Supplement: Grape Seed Extract|Dietary Supplement: Grape Seed Extract|Dietary Supplement: Grape Seed Extract Mayo Clinic 2008-02-01 2012-01-04
    NCT01185067 Diastolic Heart Failure|Hypertensive Heart Disease|Heart Failure With Preserved Ejection Fraction|Hypertension|Oxidative Stress Drug: grape seed extract (MegaNatural BP, Polyphenolics, Inc.) University of Michigan Phase 1 2010-08-01 2016-05-10
    NCT00869193 Elevated Blood Pressure Dietary Supplement: Grape seed extract|Dietary Supplement: Microcrystalline cellulose (placebo) Unilever R&D|University of Edinburgh 2009-03-01 2009-08-27
    NCT01889368 Metabolic Syndrome Dietary Supplement: Grape Seed Extract|Dietary Supplement: Placebo University of California, Davis|Illinois Institute of Technology 2012-11-01 2013-06-25
    NCT01995643 Polyphenolic Compounds and Metabolism Dietary Supplement: Active Capsule|Dietary Supplement: Placebo Capsule Institute for Food Safety and Health, United States 2013-10-01 2017-02-06
    NCT00554242 Coronary Artery Disease Dietary Supplement: Grape seed extract and ascorbic acid Boston University 2007-07-01 2009-06-16
    NCT03087903 Prostate Cancer Drug: Grape Seed Extract University of Colorado, Denver Phase 2 2017-05-01 2017-03-22
    NCT00839085 CABG-Induced Oxidative Stress Drug: GSE|Drug: Vit C (Ascorbic Acid) Tabriz University 2008-11-01 2009-02-09
    NCT02254317 Impaired Glucose Tolerance Dietary Supplement: 0 mg placebo|Dietary Supplement: 300 mg GSE|Dietary Supplement: 600 mg GSE|Dietary Supplement: 900 mg GSE Institute for Food Safety and Health, United States 2014-09-01 2017-02-06
    NCT01190358 Metabolic Syndrome Dietary Supplement: Placebo|Dietary Supplement: Meganatural Gold庐 University of California, Davis 2010-08-01 2012-05-01
    NCT02767115 Chronic Periodontitis Dietary Supplement: 2% GSE mucoadhesive gel|Other: GSE free mucoadhesive gel Riyadh Colleges of Dentistry and Pharmacy Phase 2 2015-02-01 2016-05-09
    NCT01820299 Solid Cancers Drug: Grape Seed Extract|Drug: Vitamin D Medical University of South Carolina Phase 1 2013-03-01 2017-01-30
    NCT00100893 Breast Cancer Dietary Supplement: IH636 grape seed proanthocyanidin extract City of Hope Medical Center|National Cancer Institute (NCI) Phase 1 2005-01-01 2015-06-03
    NCT00838266 Dental Plaque Drug: mouthrinse (Grape Seed Extract + nicomethanol fluorhydrate)|Other: mouthrinse containing non-active component University Hospital, Bordeaux Phase 3 2009-02-01 2009-09-22
    NCT02033941 Alzheimer's Disease Drug: Meganatural-Az Grapeseed Extract|Drug: Placebo Hillel Grossman|National Center for Complementary and Integrative Health (NCCIH)|Icahn School of Medicine at Mount Sinai Phase 2 2014-11-01 2015-11-05
    NCT03030716 Iron Deficiency Anemia|Iron-deficiency Dietary Supplement: 95% condensed proanthocyanidins from grape seed extract Kansas State University|United States Department of Agriculture Foreign Agricultural Service 2016-06-25 2017-01-24
    NCT00041223 Breast Cancer|Radiation Fibrosis Dietary Supplement: IH636 grape seed proanthocyanidin extract Royal Marsden NHS Foundation Trust|National Cancer Institute (NCI) Phase 2 2002-09-01 2013-11-05

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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