Home > Calcium Channel & > Nicardipine HCl

Nicardipine HCl

盐酸尼卡地平,RS-69216,RS 69216,RS69216

Nicardipine Hydrochloride (盐酸尼卡地平; Nicardipine; YC-93) 是一种钙通道拮抗剂，已被广泛应用于控制的严重高血压等疾病，缺血性中风，脑外伤，脑出血等。

目录号
EY1016
EY1016
纯度
99.44%
99.44%
规格
500 mg
1 g
原价
380
485
售价
380
485
库存
现货
现货
订购
订购
订购
订购
订购
订购
具体折扣请咨询客服

  • 生物活性

    Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Harino S, et al. Invest Ophthalmol Vis Sci, 1992, 33(10), 2885-2890.

    分子式
    C26H30ClN3O6    		 分子量
    515.99    		 CAS号
    54527-84-3    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    92 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02271191 Spinal Stenosis Drug: Nicardipine Yonsei University Phase 4 2012-05-01 2014-10-21
    NCT01810302 Cerebral Vasospasm Drug: Nicardipine hydrochloride|Drug: Preservative-free normal saline University of Florida Phase 2 2013-08-01 2014-08-18
    NCT00528827 Hypertension Drug: Cardene I.V. Facet Biotech Phase 2 2007-09-01 2012-03-15
    NCT00765648 Hypertensive Urgency Drug: nicardipine intravenous|Drug: Labetalol The Cleveland Clinic|EKR Therapeutics, Inc Phase 4 2008-10-01 2014-12-11
    NCT00325793 Hypertension Drug: Nicardipine OSF Healthcare System|PDL BioPharma, Inc. Phase 4 2004-01-01 2006-05-12
    NCT00409253 Hypertension During Pre-Eclampsia Drug: URAPIDIL (EUPRESSYL*)|Drug: NICARDIPINE University Hospital, Strasbourg, France Phase 3 2007-06-01 2009-02-24
    NCT02558023 Hypertension|Preeclampsia Drug: Urapidil|Drug: Nicardipine University Hospital, Strasbourg, France Phase 3 2015-09-01 2015-09-22
    NCT01872039 Hypertension Emergency|End-organ Damage Drug: Perdipine injection Astellas Pharma China, Inc.|Astellas Pharma Inc Phase 4 2013-03-01 2015-11-13
    NCT01951950 Brain Tumors Drug: Nicardipine|Drug: Esmolol Northwestern University Phase 1 2013-09-01 2014-08-28
    NCT00508118 Aortic Aneurysm, Thoracic Drug: Nicardipine|Drug: 0.9% saline Duke University Phase 2 2008-01-01 2014-07-29
    NCT01041066 Patients Who Are Intubated for General Anesthesia|Endotracheal Intubation Drug: labetalol|Drug: nicardipine Seoul National University Bundang Hospital 2009-09-01 2009-12-30
    NCT00415610 Intracerebral Hemorrhage|Hypertension|Stroke Drug: nicardipine University of Minnesota - Clinical and Translational Science Institute|National Institute of Neurological Disorders and Stroke (NINDS) Phase 1 2005-07-01 2015-08-10
    NCT01176565 Intracerebral Hemorrhage Drug: Nicardipine hydrochloride University of Minnesota - Clinical and Translational Science Institute|National Institute of Neurological Disorders and Stroke (NINDS)|Medical University of South Carolina|Johns Hopkins University|University of Michigan|Neurocritical Care Research Network|National Cerebral and Cardiovascular Center|Japan Cardiovascular Research Foundation|Beijing Tiantan Hospital|China Medical University Hospital|University Hospital Heidelberg|Seoul National University Hospital Phase 3 2011-05-01 2016-09-30
    NCT00093925 Hypertension Drug: clevidipine|Drug: nicardipine The Medicines Company Phase 3 2004-05-01 2014-05-05
    NCT01175746 Healthy Subjects Drug: Nicardipine|Drug: remifentanil Yonsei University 2010-08-01 2013-06-11
    NCT01996436 Cerebral Vasospasm Drug: Nicardipine|Drug: Verapamil|Drug: Nicardipine + Verapamil + Nitroglycerin The University of Texas Health Science Center, Houston|Yale University|University at Buffalo|Thomas Jefferson University|University of Illinois at Chicago|Mayo Clinic|Wake Forest University Health Sciences|Temple University|Geisinger Clinic|Northwell Health|University of Michigan|Brigham and Women's Hospital|Lenox Hill Hospital Phase 4 2016-08-01 2016-10-25
    NCT00490464 Subarachnoid Hemorrhage|Intracerebral Hemorrhage Drug: Nicardipine and Nipride University of Illinois at Chicago 2004-06-01 2007-06-21
    NCT01171911 Acute Coronary Syndrome|Coronary Artery Disease Drug: Nicardipine , Esmolol Nanjing Medical University Phase 4 2010-10-01 2010-07-28
    NCT01634594 Mandibular Prognathism,|Mandibular Retrognathism Drug: Group R|Drug: Group N|Drug: Group D Yonsei University Phase 4 2012-06-01 2013-02-13
    NCT02216747 Glomerular Disease Drug: prednisone 60 mg/meter square Body Surface Area|Drug: prednisone 45 mg|Drug: prednisone 30 mg Rabin Medical Center Phase 4 2014-09-01 2014-08-13
    NCT02649413 Nephrotic Syndrome, Minimal Change Drug: Prednisone Rabin Medical Center Phase 4 2016-03-01 2016-01-11

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 ：
  • 收件地址 ：
  • 电话号码 ：
  • 单位名称 ：
  • 产品货号 ：
  • 产品规格 ：
  • 发票抬头以及单位税号 ：