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Flurbiprofen

氟比洛芬,氟联苯丙酸氟联苯丙酸

Flurbiprofen (氟比洛芬) 是非甾体抗炎化合物,有退热止痛的效果。

目录号
EY0940
EY0940
纯度
99.59%
99.59%
规格
100 mg
500 mg
原价
470
680
售价
470
680
库存
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] King JG Jr, et al. Oncogene,?001, 20(47), 6864-6870.

    分子式
    C15H13FO2
    分子量
    244.26
    CAS号
    5104-49-4
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    50 mg/mL
    Water
    <1 mg/mL
    Ethanol
    50 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02206854 Healthy Volunteers Drug: R-flurbiprofen Gerd Geisslinger|Fraunhofer Institute for Molecular Biology and Applied Ecology|Goethe University Phase 1 2014-06-01 2015-09-10
    NCT00759330 Chronic Low Back Pain Drug: Placebo Tape (Arm 1)|Drug: Flurbiprofen Tape (Arm 2)|Drug: Placebo Tape (Arm 3)|Drug: Flurbiprofen Tape (Arm 4) Teikoku Pharma USA Phase 2 2007-10-01 2016-08-12
    NCT00725218 Postoperative Pain Drug: Saline|Drug: Flurbiprofen Axetil Nanjing Medical University Phase 4 2008-05-01 2008-08-05
    NCT01910090 Healthy Drug: FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET|Drug: ANTADYS 100 mg, PEPCID 20 mg Pharmaceutical Research Unit, Jordan Phase 1 2012-12-01 2013-07-24
    NCT00001724 Pain Drug: Flurbiprofen National Institute of Dental and Craniofacial Research (NIDCR)|National Institutes of Health Clinical Center (CC) Phase 2 1997-11-01 2008-03-03
    NCT01048866 Pharyngitis Drug: Placebo|Drug: Flurbiprofen Reckitt Benckiser LLC Phase 3 2009-11-01 2011-04-01
    NCT01049334 Pharyngitis Drug: Placebo|Drug: Flurbiprofen Reckitt Benckiser LLC Phase 3 2009-11-01 2011-04-01
    NCT01040286 Periodontitis Drug: Flurbiprofen|Drug: Chlorhexidine Dexcel Pharma Technologies Ltd. Phase 2 2009-08-01 2010-07-05
    NCT02367937 Healthy Drug: PRC-4016 (icosabutate) Pronova BioPharma Phase 1 2014-08-01 2015-02-13
    NCT01986361 Acute Pharyngitis|Sore Throat Drug: flurbiprofen|Drug: placebo Reckitt Benckiser LLC Phase 3 2013-10-01 2013-11-11
    NCT00425451 Periodontitis Drug: PerioChip Plus (Flurbiprofen +Chlorhexidine ), Flurbiprofen Chip, PerioChip (Chlorhexidine ) and Placebo Chip Dexcel Pharma Technologies Ltd. Phase 2 2008-08-01 2011-06-13
    NCT01998217 Pancreatic Stone Disease Drug: Remifentanil|Drug: Flurbiprofen and remifentanil Changhai Hospital Phase 4 2012-09-01 2015-02-02
    NCT02227173 Drug-drug Interaction Study Drug: BMS-986020|Drug: Montelukast|Drug: Flurbiprofen|Drug: Digoxin Bristol-Myers Squibb Phase 1 2014-09-01 2014-11-17
    NCT02569905 Postoperative Shivering Drug: parecoxib sodium|Drug: flurbiprofen|Drug: saline Guangxi Medical University Phase 4 2014-04-01 2015-10-23
    NCT02043366 Pain|Anesthesia Drug: Normal Saline|Drug: Butorphanol|Drug: Flurbiprofen axetil|Drug: Remifentanil|Drug: Sufentanil Tianjin Medical University General Hospital 2014-02-01 2015-12-08
    NCT02456844 Rheumatoid Arthritis Drug: Montelukast, Flurbiprofen, Midazolam, Digoxin, Pravastatin and BMS-986142|Drug: Methotrexate, Leucovorin and BMS-986142 Bristol-Myers Squibb Phase 1 2015-05-01 2016-01-29
    NCT01026714 Healthy Volunteers Drug: flurbiprofen|Drug: flurbiprofen, rifampicin|Drug: flurbiprofen + fluconazole University Hospital, Geneva Phase 1|Phase 2 2009-11-01 2011-01-10
    NCT03014713 Patient-Controlled Analgesia Drug: Dezocine|Drug: Flubiprofen|Drug: Dexmedetomidine Weifeng Tu|Guangzhou General Hospital of Guangzhou Military Command Phase 4 2016-09-01 2017-01-06
    NCT03090009 Peri-implant Mucositis Drug: Flurbiprofen|Drug: Placebo Oral Tablet Polak David|Hadassah Medical Organization Early Phase 1 2017-04-01 2017-03-20
    NCT02674737 Postoperative Sedation,Gastrectomy, Enhanced Recovery After Surgery Drug: dexmedetomidine, tramadol and flurbiprofen|Drug: tramadol and flurbiprofen Chinese Medical Association 2016-01-01 2016-02-03

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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