Home > others & > Oseltamivir Phosphate

Oseltamivir Phosphate

磷酸奥司他韦

Oseltamivir phosphate磷酸盐是神经氨酸酶抑制剂，具有抗流感病毒活性。

目录号
EY0857
EY0857
纯度
99.48%
99.48%
规格
100 mg
500 mg
原价
350
1200
售价
350
1200
库存
现货
现货
订购
订购
订购
订购
订购
订购
具体折扣请咨询客服

  • 生物活性

    Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] McPherson C, Warner B, Hunstad DA, Elward A, Acosta EP. Oseltamivir Dosing in Premature Infants. J Infect Dis. 2012 Aug 6.
    [2] Ison MG, Szakaly P, Shapira MY, Kriván G, Nist A, Dutkowski R. Efficacy and safety of oral oseltamivir for influenza prophylaxis in transplant recipients. Antivir Ther. 2012 Jun 22. doi: 10.3851/IMP2192.
    [3] Khandaker G et al. Clinical features, oseltamivir treatment and outcome in infants aged <12 months with laboratory-confirmed influenza A in 2009. Antivir Ther. 2011;16(7):1005-10.

    分子式
    C16H28N2O4.H3PO4    		 分子量
    410.4    		 CAS号
    204255-11-8    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    2 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01130636 Influenza Drug: Oseltamivir Pharmahungary Group|Hoffmann-La Roche Phase 4 2010-06-01 2012-10-04







    NCT01179919 Obesity Drug: Oseltamivir Manjunath Prakash Pai|Hoffmann-La Roche|University of Michigan Phase 1|Phase 2 2010-07-01 2016-12-16
    NCT01546935 Influenza Drug: Oseltamivir University of Oxford Phase 2|Phase 3 2012-12-01 2013-07-26
    NCT01456234 Influenza Drug: Oseltamivir Trial Management Group Inc.|Hoffmann-La Roche Phase 4 2011-11-01 2013-08-07
    NCT01388439 Prematurity of Fetus Drug: Oseltamivir St. Louis Children's Hospital|Genentech, Inc.|Washington University School of Medicine 2011-01-01 2011-07-05
    NCT02617784 End Stage Renal Disease Drug: Oseltamivir Hoffmann-La Roche Phase 1 2001-10-01 2016-01-17
    NCT00844155 Influenza A Virus Infection|Influenza B Virus Infection Drug: Oseltamivir 75 mg University of Manitoba|Hoffmann-La Roche 2009-03-01 2010-04-01
    NCT02717754 Healthy Volunteer Drug: Oseltamivir|Drug: Placebo Hoffmann-La Roche Phase 1 2009-12-01 2016-05-18
    NCT02561169 Influenza Drug: Oseltamivir|Other: Placebo McMaster University|University of Calgary|University of Alberta Phase 4 2015-11-01 2015-09-24
    NCT01048879 Critically Ill Renal Failure Requiring CVVHD and Oseltamivir|Critically Ill Requiring ECMO and Oseltamivir Procedure: pharmacokinetic blood sampling|Procedure: pharmacokinetic blood and dialysate sampling University of Michigan|Roche Pharma AG Phase 4 2009-10-01 2012-07-17
    NCT01902342 Healthy Drug: Oseltamivir 75 mg 1 cap Seoul National University Hospital Phase 1 2013-07-01 2014-05-15







    NCT02282384 Pulmonary Disease|Influenza Drug: oseltamivir McMaster University Phase 1 2014-10-01 2014-10-31
    NCT01049763 Healthy Drug: oseltamivir South East Asia Infectious Disease Clinical Research Network|University of Oxford Phase 1 2010-01-01 2010-10-07
    NCT01050257 Influenza Drug: Oseltamivir IV|Drug: Oseltamivir Oral Hoffmann-La Roche Phase 3 2010-01-01 2013-08-28
    NCT00298233 Influenza|Avian Influenza|Severe Influenza Drug: Oseltamivir National Institute of Allergy and Infectious Diseases (NIAID)|Wellcome Trust|World Health Organization|University of Oxford Phase 2 2006-02-01 2014-05-26
    NCT02780622 Drug Therapy, Combination Drug: Oseltamivir|Drug: Warfarin Hoffmann-La Roche Phase 4 2008-02-01 2016-09-19
    NCT00540501 Healthy Subjects Drug: Oseltamivir and Intravenous Zanamivir GlaxoSmithKline Phase 1 2007-10-01 2010-05-27
    NCT01715909 Influenza Drug: Oseltamivir Hoffmann-La Roche Phase 1 2014-01-22 2017-03-10
    NCT01010087 Influenza A Virus Drug: Oseltamivir University of Manitoba|Hoffmann-La Roche Phase 2 2009-11-01 2011-06-09
    NCT01249833 Influenza Drug: Oseltamivir Trial Management Group Inc.|Hoffmann-La Roche Phase 4 2010-11-01 2017-01-18
    NCT01052961 Influenza|Respiratory Tract Infections Drug: Oseltamivir Chinese University of Hong Kong|Hoffmann-La Roche Phase 4 2010-01-01 2012-07-19
    NCT01443806 Metabolic Disease Drug: Oseltamivir University of Oxford|South East Asia Infectious Disease Clinical Research Network Phase 4 2011-07-01 2012-06-28

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 ：
  • 收件地址 ：
  • 电话号码 ：
  • 单位名称 ：
  • 产品货号 ：
  • 产品规格 ：
  • 发票抬头以及单位税号 ：