Levonorgestrel

左炔诺孕酮

Levonorgestrel 是一种人工合成的孕激素,是一些激素避孕药中的活性成分。

目录号
EY0855
EY0855
纯度
99.66%
99.66%
规格
100 mg
500 mg
原价
260
420
售价
260
420
库存
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Levonorgestrel is a female hormone that prevents ovulation.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Sitruk-Ware et al (2006) New progestagens for contraceptive use. Hum.Reprod.Update 12 169.

    分子式
    C21H28O2
    分子量
    312.45
    CAS号
    797-63-7
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    44 mg/mL
    Water
    <1 mg/mL
    Ethanol
    2 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    HIV|Contraception Drug: Levonorgestrel|Drug: Efavirenz University of Nebraska|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|Infectious Diseases Institute, Uganda|University of Liverpool|Feinberg School of Medicine, Northwestern University Phase 2 2016-11-01 2016-10-24
    Adenomyosis Procedure: Placement of levonorgestrel-releasing intrauterine system Peking Union Medical College Hospital 2006-12-01 2017-01-19
    Epilepsy|Contraception Drug: levonorgestrel IUS Columbia University|Bayer Phase 4 2011-08-01 2015-12-14
    Pregnancy, Unplanned|Pregnancy; Accident Drug: Ulipristal acetate|Device: levonorgestrel IUS Washington University School of Medicine|William and Flora Hewlett Foundation|University of Colorado, Denver|Planned Parenthood Federation of America|University of Rochester 2012-12-01 2015-12-09
    HIV|Contraception Drug: Levonorgestrel|Drug: Nevirapine|Drug: Efavirenz University of Nebraska|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|Makerere University|University of Liverpool Phase 2 2013-06-01 2016-03-31
    Obesity Drug: Levonorgestrel 1.5mg by mouth once University of Southern California|Society of Family Planning 2013-04-01 2016-10-24
    Contraception Drug: Levonorgestrel IUD University of Utah|Society of Family Planning|University of New Mexico Phase 4 2014-01-01 2017-02-02
    Contraception Device: Levonorgestrel-releasing IUD (Mirena) University of Pittsburgh 2007-05-01 2016-05-17
    Emergency Contraception Drug: Copper IUD|Drug: Levonorgestrel IUD University of Utah 2013-07-01 2016-08-04
    Contraception Drug: Levonorgestrel IUS (Mirena, BAY86-5028) Bayer 2007-05-01 2014-01-08
    Healthy Drug: levonorgestrel FHI 360 Phase 3 2010-01-01 2013-08-22
    Endometriosis Drug: Levonorgestrel|Drug: Etonogestrel University of Campinas, Brazil Phase 4 2015-07-01 2015-06-23
    Contraception Drug: LNG20|Drug: Mirena Medicines360 Phase 3 2009-11-01 2016-12-14
    Contraceptive Implant Utilization|Lactation Device: Jadelle|Device: Jadelle University of California, San Francisco|Mulago Hospital, Uganda|Makerere University Phase 4 2015-01-01 2016-07-15
    Pregnancy Drug: Copper T380 IUD|Drug: Oral levonorgestrel University of Utah|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|Society of Family Planning 2009-10-01 2017-02-02
    Contraception Dietary Supplement: Placebo Control (Placebo Herb)|Dietary Supplement: St. John's Wort|Drug: Levonorgestrel University of Utah|National Center for Complementary and Integrative Health (NCCIH) Phase 4 2005-08-01 2015-07-15
    Hyperplasia|Endometrial Cancer Device: Levonorgestrel IUD M.D. Anderson Cancer Center Phase 2 2008-11-01 2016-09-07
    Healthy Device: Levonorgestrel-releasing intrauterine system (LNG-IUS)|Device: Levonorgestrel-releasing intrauterine system (LNG-IUS) University of Chicago 2007-05-01 2013-04-01
    Contraception Drug: Levonorgestrel IUS (Mirena, BAY86-5028) Bayer Phase 3 2016-12-01 2017-03-01
    Estimating Rates of Expulsion Device: Levonorgestrel Intrauterine Device Maine Medical Center Research Institute Phase 4 2010-08-01 2011-08-01
    Contraception Drug: Levonorgestrel (BAY98-7196) Bayer Phase 3 2015-05-01 2016-08-17







    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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