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Piperacillin Sodium

哌拉西林钠,CL227193,Sodium piperacillin,CL-227193,CL 227193,

Piperacillin钠是一种半合成的广谱青霉素类抗菌剂, 肠胃用药。

目录号
EY0849
EY0849
纯度
99.15%
99.15%
规格
50 mg
100 mg
原价
330
580
售价
330
580
库存
现货
现货
订购
订购
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  • 生物活性

    Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Williamson R, et al. Antimicrob Agents Chemother, 1980, 18(4), 629-637.

    分子式
    C23H26N5NaO7S
    分子量
    539.54
    CAS号
    59703-84-3
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    100 mg/mL
    Water
    100 mg/mL
    Ethanol
    100 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01760109 Respiratory Tract Infections|Urinary Tract Infections Drug: Piperacillin Sodium and Sulbactam Sodium Xiangbei Welman Pharmaceutical Co., Ltd Phase 4 2011-07-01 2012-12-30
    NCT02466438 Infection Drug: Piperacillin-tazobactam St. Justine's Hospital Phase 1 2016-01-01 2016-04-18
    NCT02730624 Early Phase of Severe Sepsis and Septic Shock Drug: Piperacillin-tazobactam Sutep Jaruratanasirikul|Prince of Songkla University Phase 4 2014-03-01 2016-03-31
    NCT00703144 Diffusive and Convective Clearance|Body Clearance|Piperacillin Tazocilline Concentrations (Cmin) Drug: piperacillin/tazobactam|Procedure: Pharmacokinetic University Hospital, Toulouse Phase 4 2008-06-01 2013-01-23
    NCT01897831 Respiratory Tract Infections|Urinary Tract Infections Drug: xin te mie Xiangbei Welman Pharmaceutical Co., Ltd Phase 4 2011-08-01 2013-07-09
    NCT02753946 Urinary Tract Infection Symptomatic|Acute Pyelonephritis|Urinary Tract Infection Complicated Drug: ZTI-01|Drug: Piperacillin-tazobactam Zavante Therapeutics|Medpace, Inc. Phase 2|Phase 3 2016-04-01 2017-01-12
    NCT01198925 Infectious Disease Drug: piperacillin continuous infusion|Drug: piperacillin extended infusion University Hospital, Ghent Phase 4 2010-09-01 2014-12-04
    NCT01923363 Obesity Drug: Piperacillin/Tazobactam Standard Dose|Drug: Piperacillin/Tazobactam High Dose Loma Linda University 2014-01-01 2016-09-13
    NCT02437045 Bloodstream Infections Drug: Meropenem|Drug: Piperacillin-tazobactam combination product The University of Queensland Phase 4 2015-04-01 2016-11-13
    NCT01694069 Cystic Fibrosis Drug: Piperacillin-tazobactam combination product West Virginia University Phase 4 2012-09-01 2014-03-14
    NCT02306928 Septic Shock Other: Blood draw University of Aarhus 2014-09-01 2016-02-09
    NCT01796717 Nosocomial Pneumonia Drug: C Group|Drug: E Group Tianjin Medical University Cancer Institute and Hospital|Pfizer Phase 2|Phase 3 2012-03-01 2016-02-14
    NCT00389987 Complicated Intra-Abdominal Infections Drug: MK0826, /Duration of Treatment : 8 Weeks|Drug: Comparator : piperacillin sodium (+) tazobactam sodium /Duration of Treatment : 8 Weeks Merck Sharp & Dohme Corp. Phase 3 2001-09-01 2017-02-16
    NCT01983787 Cystic Fibrosis University of Aarhus Phase 4 2013-07-01 2015-11-06
    NCT00873327 Sepsis Drug: piperacillin-tazobactam Phillip Brian Smith|Duke University Phase 1 2009-10-01 2013-05-29
    NCT02176122 Bloodstream Infections Drug: Meropenem|Drug: Piperacillin-tazobactam combination product The University of Queensland|International Society of Chemotherapy|Australian Society for Antimicrobials|Queensland Clinical Trials & Biostatistics Centre|Australasian Society for Infectious Diseases Phase 4 2014-02-01 2016-11-15
    NCT01714557 Neutropenia|Hematopoietic Stem Cell Transplantation Drug: Piperacillin|Drug: Piperacillin-tazobactam combination product Chinese PLA General Hospital 2012-09-01 2012-10-25
    NCT01370616 Infection; Diabetic Foot Drug: Ertapenem sodium|Drug: Piperacillin/tazobactam sodium|Drug: Piperacillin/tazobactam-matching placebo|Drug: Amoxicillin/clavulunate potassium Merck Sharp & Dohme Corp. Phase 3 2011-09-01 2017-02-17
    NCT00629135 Abscess, Intra-Abdominal Drug: Moxifloxacin/Metronidazole or Piperacillin/Tazobactam Hannover Medical School|Bayer Phase 3 2005-11-01 2011-06-21
    NCT01517815 Septic Shock Drug: Doripenem or Piperacillin/Tazobactam|Drug: Doripenem or Piperacillin/Tazobactam University Hospital, Montpellier 2012-02-01 2016-11-28
    NCT00816790 Septic Shock|Acute Renal Failure Drug: Piperacillin/Tazobactam|Drug: Piperacillin/Tazobactam Fraser Health Phase 4 2009-01-01 2015-09-10

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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