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Cephalexin

头孢氨苄,苯甘头孢菌素,Cefalexin,Cephacillin,Keflex

Cefalexin是头孢菌素类抗生素。

目录号
EY0782
EY0782
EY0782
纯度
99.39%
99.39%
99.39%
规格
50 mg
100 mg
500 mg
原价
180
230
350
售价
180
230
350
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Cephalexin is an antibiotic that can treat a number of bacterial infections.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Watanabe S, et al. J Pharmacol Exp Ther, 2010, 334(2), 651-656.
    [2] Tanrisever B, et al. Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine. Drugs. 1986;32 Suppl 3:1-16.

    分子式
    C16H17N3O4S
    分子量
    347.39
    CAS号
    15686-71-2
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    2 mg/mL
    Water
    10 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02100826 Healthy Volunteers Drug: Cephalexin Eli Lilly and Company|Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V. Phase 1 2014-04-01 2015-05-08
    NCT02123446 Healthy Volunteers Drug: Cephalexin Eli Lilly and Company|Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V. Phase 1 2014-04-01 2015-06-19
    NCT02123459 Healthy Volunteers Drug: Cephalexin Eli Lilly and Company|Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V. Phase 1 2014-05-01 2015-05-08
    NCT02123472 Healthy Volunteers Drug: Cephalexin Eli Lilly and Company|Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V. Phase 1 2014-05-01 2015-06-19
    NCT02490670 Healthy Drug: Cephalexin Eli Lilly and Company|Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V. Phase 1 2015-07-01 2016-09-05
    NCT01029782 Cellulitis Drug: IV cefazolin plus oral probenecid and placebo cephalexin|Drug: Oral cephalexin and saline IV plus probenecid placebo Kelowna General Hospital|Canadian Society of Hospital Pharmacists|Capital Health, Canada|Interior Health Authority, Canada Phase 2 2010-05-01 2015-01-13
    NCT01767584 Infections, Respiratory Tract Drug: Cephalexin 1g tablets|Drug: Cephalexin 1g tablets GlaxoSmithKline Phase 1 2009-04-01 2013-01-10
    NCT01767532 Infections, Respiratory Tract Drug: Cephalexin 125 mg/5ml|Drug: Cephalexin 125 mg/5ml GlaxoSmithKline Phase 1 2011-01-01 2013-01-10
    NCT00352612 Staphylococcal Infection|Abscess|Staphylococcal Skin Infection|Folliculitis Drug: clindamycin|Drug: cephalexin Aaron Chen|Thrasher Research Fund|Johns Hopkins University Phase 4 2006-09-01 2013-04-01
    NCT01767571 Infections, Respiratory Tract Drug: Cephalexin 125 mg/5ml|Drug: Cephalexin 250mg/5ml GlaxoSmithKline Phase 1 2011-01-01 2013-01-10
    NCT00234949 Mild to Moderate Uncomplicated Skin and Skin Structure Infections Drug: cefdinir|Drug: cephalexin Abbott Phase 4 2005-03-01 2007-10-23
    NCT00003824 Bladder Cancer Drug: cephalexin|Procedure: surgical procedure|Drug: Ciprofloxacin Southwest Oncology Group|National Cancer Institute (NCI) Phase 3 1999-04-01 2012-03-07
    NCT01194115 Surgical Site Infection in Obese Women Undergoing C-section Drug: cephalexin & metronidazole|Drug: placebo University of Cincinnati 2010-09-01 2011-11-10
    NCT00300092 Finger Injuries Drug: Cepahlexin (drug) Children's Hospital Los Angeles Phase 2 2000-09-01 2015-04-16
    NCT02911662 Bacteriuria (Asymptomatic) in Pregnancy Drug: Cephalexin|Drug: Nitrofurantoin Saint Joseph Mercy Health System 2016-09-01 2016-09-20
    NCT01823523 Dentofacial Deformity Drug: Cefazolin, Cephalexin, Clindamycin Atlantic Center for Oral and Maxillofacial Surgery 2013-06-01 2015-01-12
    NCT00676130 Cellulitis Drug: trimethoprim-sulfamethoxazole|Drug: Cephalexin Brigham and Women's Hospital 2007-05-01 2012-08-12
    NCT00957827 Through-and-through Lip Lacerations Drug: keflex|Drug: placebo University of Pennsylvania 2009-08-01 2015-12-09
    NCT01912651 Facial Defect Drug: cephalexin University of Michigan Phase 4 2013-07-01 2016-05-23

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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