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Neomycin sulfate

硫酸新霉素

Neomycin sulfate是氨基糖苷类抗生素,是钙离子通道抑制剂。

目录号
EY0734
EY0734
EY0734
EY0734
纯度
99.57%
99.57%
99.57%
99.57%
规格
100 mg
500 mg
1 g
5 g
原价
120
280
320
385
售价
120
280
320
385
库存
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Neomycin sulphate is an aminoglycoside antibiotic, used to treat bacteria infections.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Stage TK, et al. RNA,1995,(1), 95-101.
    [2] Vergara, J., et al. 1985. Proc. Natl. Acad. Sci. U.S.A. 82: 6352-6356.
    [3] Gabev, E., et al. 1989. Biochim. Biophys. Acta. 979: 105-112.
    [4] Woegerbauer, M., et al. 2000. J. Antibiot. 53: 276-285.
    [5] Liscovitch, M., et al. 1991. Biochem. J. 279: 319-321.

    分子式
    C23H46N6O13
    分子量
    614.64
    CAS号
    1405-10-3
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    <1 mg/mL
    Water
    ≥50 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02001909 Neoplasms Drug: Regorafenib (Stivarga, BAY73-4506)|Drug: Neomycin Bayer Phase 1 2013-12-01 2015-08-12
    NCT00945334 Constipation-predominant Irritable Bowel Syndrome Drug: Neomycin|Drug: Placebo|Drug: Rifaximin Mark Pimentel, MD|Valeant Pharmaceuticals International, Inc.|Cedars-Sinai Medical Center 2009-08-01 2015-07-17
    NCT00857688 Aphtous Ulcers Drug: Bismu-Jet|Other: Placebo Azidus Brasil Phase 3 2011-05-01 2013-02-22
    NCT02472600 Intestinal Colonization With Multidrug-resistant Bacteria Drug: Colistin|Drug: Neomycin|Drug: Fecal microbiota transplantation (FMT)|Drug: Omeprazole Stephen Harbarth|European Commission|University Hospital, Geneva Phase 2 2016-02-01 2016-09-29
    NCT03042091 Colorectal Neoplasms|Diverticulitis|Inflammatory Bowel Diseases|Surgical Site Infection Drug: Polyethylene Glycol|Drug: Neomycin|Drug: Metronidazole Hydrochloride|Procedure: Therapeutic Conventional Surgery Sidney Kimmel Cancer Center at Thomas Jefferson University|Thomas Jefferson University Early Phase 1 2016-09-01 2017-02-14
    NCT02682485 Anastomotic Leak|Rectal Cancer Drug: Cipro, metronidazole, neomycin combo|Procedure: Serial Endoscopic Surveillance|Drug: Saline University of Chicago Phase 2 2017-01-01 2017-01-10
    NCT00534391 Hordeolum Drug: neomycin sulfate, polymyxin B sulfate and gramicidin|Drug: Artificial tear Chulalongkorn University Phase 3 2007-09-01 2010-11-22
    NCT01638429 Diabetes|Obesity Drug: Neomycin and Rifaximin Cedars-Sinai Medical Center|American Diabetes Association 2012-07-01 2014-04-01
    NCT00166868 Biliary Atresia Drug: Lactobacillus casei rhamnosus (Lcr35)|Drug: Neomycin National Taiwan University Hospital 2003-12-01 2013-08-19
    NCT01798537 Bacteremia Associated With Intravascular Line|Ventilator Associated Pneumonia|Bacteremia Drug: Neomycin Colistin Nystatin Vancomycin Rambam Health Care Campus Phase 2|Phase 3 2013-06-01 2013-02-25
    NCT01227863 Bacterial Conjunctivitis|Acute Drug: MAXINOM庐|Drug: Maxitrol庐 Azidus Brasil Phase 3 2011-02-01 2010-10-22
    NCT00058617 Epstein-Barr Virus-Related Hodgkin Lymphoma|Epstein-Barr Virus-Related Non-Hodgkin Lymphoma|EBV Positive Plasma Cell Neoplasm Biological: Injection of EBV Specific CTLs Baylor College of Medicine|Texas Children's Hospital|The Methodist Hospital System|Center for Cell and Gene Therapy, Baylor College of Medicine Phase 1 1996-01-01 2017-02-13
    NCT02444481 Vaginitis Drug: Polygynax combinaison of polymyxin, Neomycin and Nystatin Laboratoire Innotech International Phase 4 2009-04-01 2015-05-11
    NCT02168478 Allergy Drug: Neo-Synalar Cream|Other: Sodium Lauryl Sulfate Aqueous Solution (0.40%)|Other: Saline Noah Rosenberg, MD|Medimetriks Pharmaceuticals, Inc Phase 4 2014-06-01 2015-11-05
    NCT02652637 Colorectal Surgery Drug: neomycin, metronidazole, polyethylene glycol (PEG) Helsinki University Central Hospital Phase 4 2016-02-01 2016-12-04
    NCT03006809 Ulcerative Colitis Biological: Fecal Microbiota Transplantation (FMT), OpenBiome|Other: pretreatment antibiotics Najwa Elnachef|University of California, San Francisco Phase 1 2017-04-01 2017-03-16
    NCT02582255 Poliomyelitis Biological: Sabin mOPV2 Fidec Corporation|Bill and Melinda Gates Foundation Phase 4 2015-11-01 2015-10-19

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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