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Hematoxylin

苏木精,Hydroxybrazilin

Hematoxylin易与某些金属离子，尤其是Fe（III）和Al（Ⅲ）盐，形成有色络合物。

目录号
EY0696
EY0696
EY0696
纯度
99.53%
99.53%
99.53%
规格
5 mg
25 mg
100 mg
原价
98
120
162
售价
98
120
162
库存
现货
现货
现货
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  • 生物活性

    Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Godwin A, J Pharm Clin Sci, 2011, 1, 24-34.
    [2] EF Kingston, et al. Vascular invasion is underrecognized in colorectal cancer using conventional hematoxylin and eosin staining. 《Diseases of the Colon & Rectum》, 2007, 50(11):1867-1872
    [3] HR Zare, et al. Simultaneous determination of ascorbic acid, adrenaline and uric acid at a hematoxylin multi-wall carbon nanotube modified glassy carbon electrode. Sensors & Actuators B Chemical, 2010, 143(2):666-672

    分子式
    		分子量
    		 CAS号
    517-28-2    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    60 mg/mL    		 Water
    60 mg/mL    		 Ethanol
    60 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01136369 Breast Neoplasms|Breast Diseases Device: OSNA Breast Cancer System Sysmex America, Inc. 2007-02-01 2010-06-02
    NCT02845180 Obesity Procedure: Adipose Allograft Extracellular Matrix (AAM) Injection Musculoskeletal Transplant Foundation 2016-11-01 2016-11-17
    NCT01140776 Breast Neoplasms|Breast Diseases Sysmex America, Inc. 2010-11-01 2011-06-06
    NCT00847340 Genital Warts|HPV Infections Procedure: Biopsy Excisional La Fundacion para la Investigacion y el Desarrollo 2009-12-01 2012-03-19
    NCT02638181 Open-angle Glaucoma Procedure: trabeculectomy Lv Yingjuan|Tianjin Medical University Eye Hospital 2013-07-01 2017-01-08
    NCT00551278 Breast Cancer Device: GeneSearch鈩?Breast Lymph Node (BLN) Assay Janssen Diagnostics, LLC 2007-10-01 2016-01-11
    NCT02745379 Alveolar Bone Loss Procedure: BFPSCs+ DFDBA+ PRF|Procedure: DFDBA + PRF Shahid Beheshti University of Medical Sciences Phase 1 2016-01-01 2016-10-13
    NCT02745366 Alveolar Bone Loss|Atrophy Procedure: BFPSC+FDBA+PRF|Procedure: FDBA+PRF Shahid Beheshti University of Medical Sciences Phase 1 2016-01-01 2016-10-13
    NCT03023475 CABG Graft Integrity Device: LigaSure endoscopic vessel harvesting|Device: TLS2 endoscopic vessel harvesting Kerckhoff Klinik 2017-01-01 2017-01-17
    NCT02834429 Celiac Disease Sheffield Teaching Hospitals NHS Foundation Trust 2010-02-01 2016-08-01
    NCT01584414 Cervical Cancer Meir Medical Center Phase 1 2007-10-01 2012-04-24
    NCT00943891 Colorectal Cancer|Nasopharyngeal Cancer Procedure: Tumor biopsies National University Hospital, Singapore 2008-07-01 2014-01-21
    NCT01064609 Interstitial Lung Disease Procedure: Biopsy by cryoprobes|Procedure: Biopsy with conventional forceps Fundaci贸 Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 2011-06-01 2013-01-21
    NCT02266420 Triple Negative Breast Cancers Without Lymph-node Involvement and < or = 30 mm Procedure: Blood samples of 10 mL Institut Claudius Regaud 2014-10-01 2015-05-26
    NCT02057926 Ridge Preservation Technique Drug: The effect of tetracycline in degradation and permeability of collagen membranes. Universitat Internacional de Catalunya Phase 2 2009-11-01 2014-02-05
    NCT02850783 Sentinel Lymph Node Procedure: 89Zr-nanocoll and Indocyanine Green VU University of Amsterdam Phase 2|Phase 3 2015-03-01 2016-07-29
    NCT01810640 Brain Death|Liver Disease Procedure: Percutaneous Liver Biopsy Rutgers, The State University of New Jersey 2013-02-01 2015-05-11
    NCT02495532 Colorectal Neoplasms|Neoplasm Metastasis Other: Lymph node clearing technique with Carnoy solution|Other: Lymph node clearing technique with GEWF solution Hospital Moinhos de Vento|Federal University of Health Science of Porto Alegre 2015-03-01 2015-07-08
    NCT01902589 Abdominal Pain|Children|Bacterial Infection Due to Helicobacter Pylori (H. Pylori)|Antibiotic Resistant Strain Other: Helicobacter Pylori Culture HaEmek Medical Center, Israel 2010-12-01 2015-08-30
    NCT00042926 Head and Neck Cancer Other: immunohistochemistry staining method|Procedure: conventional surgery|Procedure: lymphangiography|Procedure: radionuclide imaging|Procedure: sentinel lymph node biopsy|Radiation: technetium Tc 99m sulfur colloid Alliance for Clinical Trials in Oncology|National Cancer Institute (NCI) 2002-05-01 2016-12-05
    NCT01140763 Breast Neoplasms|Breast Diseases Device: Sysmex's 5-blade lymph node cutter Sysmex America, Inc. 2010-08-01 2010-08-27
    NCT00003854 Breast Cancer Other: immunohistochemistry staining method|Procedure: lymphangiography|Procedure: sentinel lymph node biopsy|Procedure: therapeutic conventional surgery|Radiation: whole breast irradiation Alliance for Clinical Trials in Oncology|National Cancer Institute (NCI) Phase 3 1999-04-01 2016-07-12

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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