Home > others & > Nitazoxanide

Nitazoxanide

硝唑尼特,NTZ,Alinia,NSC 697855,NSC697855,NSC-697855,

Nitazoxanide是抗原生动物化合物,对犬流感病毒的IC50为0.17 到 0.21μM。

目录号
EY0675
EY0675
EY0675
EY0675
纯度
99.53%
99.53%
99.53%
99.53%
规格
1 mg
5 mg
10 mg
50 mg
原价
125
262
432
1300
售价
125
262
432
1300
库存
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Theodos CM, et al. Antimicrob Agents Chemother, 1998, 42(8), 1959-1965.
    [2] Stockis, A., et al.: Int. J. Clin. Pharmacol. Ther., 34, 349 (1996)
    [3] Dubreuil, L., et al.: Antimicrob. Ag. Chemother., 40, 2266 (1996)

    分子式
    C12H9N3O5S
    分子量
    307.28
    CAS号
    55981-09-4
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    62 mg/mL
    Water
    <1 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01326338 Diarrhea Drug: Nitazoxanide Romark Laboratories L.C. Phase 3 2005-03-01 2011-03-29
    NCT01197157 Hepatitis C Drug: Placebo|Drug: Nitazoxanide National Liver Institute, Egypt Phase 2|Phase 3 2010-09-01 2014-09-27
    NCT01328925 Rotavirus Infection|Viral Gastroenteritis Due to Rotavirus Drug: Nitazoxanide Romark Laboratories L.C. Phase 2 2005-12-01 2011-04-01
    NCT00763568 Chronic Hepatitis C Drug: Nitazoxanide|Biological: Peginterferon alfa-2a Romark Laboratories L.C. Phase 2 2006-08-01 2008-09-26
    NCT02612922 Influenza Drug: Nitazoxanide|Drug: Placebo Romark Laboratories L.C. Phase 3 2015-12-01 2016-08-24
    NCT02334163 Hepatic Encephalopathy Drug: Nitazoxanide|Drug: Oral lactulose|Drug: Metronidazole|Drug: Rifaximine Ain Shams University|Al-Azhar University Phase 2 2014-12-01 2015-01-07
    NCT02452905 Bronchiolitis Drug: Nitazoxanide|Drug: Placebo (for Nitazoxanide) Telethon Kids Institute Phase 2 2016-12-01 2016-05-03
    NCT01074203 Hepatitis C Recurrence Drug: Nitazoxanide Mayo Clinic Phase 1 2009-02-01 2012-07-27
    NCT01185028 Hepatitis C Infection|HIV Infection Drug: Nitazoxanide With Pegylated Interferon And Ribavirin National Institutes of Health Clinical Center (CC) Phase 1|Phase 2 2010-08-01 2013-05-16
    NCT02165813 Gastroenteritis Drug: Nitazoxanide|Drug: Placebo Telethon Kids Institute|The University of Western Australia|Menzies School of Health Research Phase 2 2014-11-01 2016-05-03
    NCT00130390 Crohn's Disease Drug: Nitazoxanide|Other: Placebo Romark Laboratories L.C. Phase 2 2005-08-01 2012-05-30
    NCT02684240 Tuberculosis Drug: Nitazoxanide|Other: Control Weill Medical College of Cornell University Phase 2 2016-02-01 2017-01-12
    NCT01227421 Influenza Drug: Nitazoxanide|Drug: Nitazoxanide|Drug: Placebo Romark Laboratories L.C. Phase 2|Phase 3 2010-12-01 2014-01-08
    NCT01056380 Influenza Drug: Nitazoxanide|Drug: Placebo Romark Laboratories L.C. Phase 2 2010-01-01 2012-05-30
    NCT02464124 Encephalopathy, Hepatic Drug: Nitazoxanide|Drug: Lactulose Sherief Abd-Elsalam|Tanta University Phase 2|Phase 3 2015-05-01 2016-10-17
    NCT00302640 Rotavirus Infection|Adenoviridae Infection|Norovirus Infection Drug: Alinia (nitazoxanide) Romark Laboratories L.C. Phase 2|Phase 3 2005-02-01 2012-05-30
    NCT00384527 Clostridium Infections Drug: Nitazoxanide|Drug: Vancomycin Romark Laboratories L.C. Phase 3 2006-12-01 2015-05-04
    NCT01610245 Influenza Drug: Nitazoxanide|Drug: Oseltamivir|Drug: Placebo Oral Tablet|Drug: Placebo Oral Capsule Romark Laboratories L.C. Phase 3 2013-03-01 2017-02-27
    NCT01770483 Hepatitis C, Chronic|DIABETES MELLITUS Type 2 Drug: nitazoxanide|Drug: conventional interferon alfa|Drug: Ribavirin Services Institute of Medical Sciences, Pakistan|Getz Pharma Phase 4 2011-07-01 2013-09-15

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 :
  • 收件地址 :
  • 电话号码 :
  • 单位名称 :
  • 产品货号 :
  • 产品规格 :
  • 发票抬头以及单位税号 :