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Clobetasol propionate

丙酸氯倍他索,CGP9555,CCl 4725,CGP 9555,CGP-9555,CCl4725,CCl-4725,

Clobetasol propionate为抗炎皮质类固醇，可作用于各种皮肤病。

目录号
EY0674
EY0674
EY0674
纯度
99.41%
99.41%
99.41%
规格
100 mg
200 mg
500 mg
原价
620
935
1800
售价
620
935
1800
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
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  • 生物活性

    Clobetasol propionate is an anti-inflammatory corticosteroid used to treat various skin disorders.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Melian EB, Spencer CM, Jarvis B. Am J Clin Dermatol. 2:89-92; discussion 93 (2001)
    [2] Bernstein EF, Kantor G, Howe N et al. J Am Acad Dermatol. 31:307-11 (1994).

    分子式
    C25H32ClFO5    		 分子量
    466.97    		 CAS号
    25122-46-7    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    90 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    20 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01703325 Psoriatic Nails Drug: 0.1% triamcinolone , 0.05% clobetasol propionate ointment Mahidol University Phase 4 2010-11-01 2012-10-07
    NCT00733954 Plaque Psoriasis Drug: clobetasol propionate spray|Drug: clobetasol propionate ointment Galderma Laboratories, L.P. Phase 4 2007-08-01 2014-04-28
    NCT00842153 Psoriasis Drug: Clobetasol propionate foam|Drug: Vehicle foam Stiefel, a GSK Company|GlaxoSmithKline Phase 4 2007-11-01 2011-12-21
    NCT00828464 Hand Dermatosis Drug: clobetasol propionate Stiefel, a GSK Company|GlaxoSmithKline Phase 4 2008-10-01 2012-09-21
    NCT00864500 Healthy Drug: Clobetasol Propionate 0.05% lotion, single exposure|Drug: Clobex TM 0.05% Lotion, single exposure Actavis Inc. Phase 1 2005-11-01 2010-08-13
    NCT00436540 Psoriasis Drug: Clobetasol Propionate 0.05% Spray|Drug: Clobetasol Propionate 0.05% Foam Galderma Laboratories, L.P. Phase 4 2006-03-01 2008-03-27
    NCT01111981 Alopecia Drug: Clobetasol Propionate 0.05% Emollient Foam Callender Center for Clinical Research Phase 4 2009-10-01 2010-04-27
    NCT00988637 Plaque Psoriasis Drug: Vectical鈩?Ointment weekdays and Clobex庐 Spray weekends regimen|Drug: Clobex庐 Spray morning and Vectical鈩?Ointment evening regimen Galderma Laboratories, L.P. Phase 4 2009-10-01 2012-09-21
    NCT01893567 Plaque Psoriasis Drug: Clobex Spray Galderma Laboratories, L.P. Phase 4 2013-07-01 2014-09-03
    NCT00881868 Scalp Psoriasis Drug: clobetasol propionate spray 0.05%|Drug: Vehicle spray Galderma Laboratories, L.P. Phase 4 2009-04-01 2012-09-21
    NCT00852761 Plaque-Type Psoriasis Drug: Olux-E Foam|Drug: Clobex lotion Stiefel, a GSK Company|GlaxoSmithKline Phase 4 2009-03-01 2012-04-19
    NCT02573883 Vulvar Lichen Sclerosus Device: Radiofrequency Carbon Dioxide Laser|Drug: Clobetasol Propionate 0.05% ointment Medstar Health Research Institute Phase 3 2015-10-01 2016-04-18
    NCT00864240 Healthy Drug: Clobex TM (Clobetasol) 0.05% Lotion, single exposure Actavis Inc. Phase 1 2005-10-01 2010-08-13
    NCT00658788 Psoriasis Drug: clobetasol propionate spray 0.05%|Drug: calcitriol ointment Galderma Laboratories, L.P. Phase 3 2008-03-01 2014-08-12
    NCT00803439 Healthy Drug: Clobetasol Propionate 0.05% Foam-Reference Product|Drug: Clobetasol Propionate 0.05% Foam-Test product Perrigo Company 2005-04-01 2012-03-15
    NCT01745133 Psoriasis Drug: vehicle foam|Drug: calcipotriene|Drug: calcipotriene + clobetasol propionate Leon Kircik, M.D.|Stiefel, a GSK Company|Derm Research, PLLC Phase 4 2013-01-01 2016-11-15
    NCT00757874 Vulvar Lichen Sclerosus Drug: Tacrolimus cream|Drug: Clobetasol cream Deana Funaro|Astellas Pharma Inc|St. Justine's Hospital Phase 2 2006-04-01 2015-09-05
    NCT01126255 Vulvar Lichen Sclerosus Drug: Clobetasol propionate 0.05%|Drug: Progesterone 8% University Hospital Inselspital, Berne|University of Bern Phase 2 2011-03-01 2014-10-07
    NCT01557517 Oral Chronic Graft vs Host Disease Drug: Clobetasol Oral Rinse|Drug: Placebo oral rinse National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC) Phase 2 2012-01-25 2017-03-02
    NCT00437216 Psoriasis Drug: Clobetasol Propionate, 0.05%|Drug: Clobetasol propionate, 0.05% Spray Galderma Laboratories, L.P. Phase 4 2006-02-01 2008-03-27
    NCT01323673 Dermatitis, Chronic Drug: clobetasol propionate 0.05%|Drug: Vehicle / Placebo Stiefel, a GSK Company|GlaxoSmithKline Phase 4 2010-11-01 2016-11-29
    NCT00862654 Scalp Seborrheic Dermatitis Drug: clobetasol propionate shampoo (4/week) - ketoconazole shampoo (2/week)|Drug: clobetasol propionate shampoo (2/week) - ketoconazole shampoo (2/week)|Drug: clobetasol propionate shampoo (2/week)|Drug: ketoconazole shampoo (2/week) Galderma Phase 3 2009-03-01 2011-08-31
    NCT00437255 Plaque Psoriasis Drug: Clobetasol Propionate, 0.05%|Drug: Calcipotriene and betamethasone dipropionate ointment Galderma Laboratories, L.P. Phase 4 2006-08-01 2008-04-03

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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