Home > others & > Trimethoprim

Trimethoprim

甲氧苄啶,BW 56-72,NIH 204,NSC-106568,NIH204,NIH-204,NIH-204,NIH204

Trimethoprim是抗菌素，可作用于泌尿系统感染。

目录号
EY0601
EY0601
纯度
99.25%
99.25%
规格
25 mg
500 mg
原价
128.00
390
售价
128.00
390
库存
现货
现货
订购
订购
订购
订购
订购
订购
具体折扣请咨询客服

  • 生物活性

    Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Vouloumanou EK, et al. Int J Antimicrob Agents, 2011, 38(3), 197-216.
    [2] Rajith, L. and Kumar, K.G. 2010. Drug Test Anal. 2: 436-441.
    [3] Zander, J., et al. 2010. Int. J. Antimicrob. Agents. 36: 562-565.

    分子式
    C14H18N4O3    		 分子量
    290.32    		 CAS号
    738-70-5    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    50 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01167452 Obesity|Pharmacokinetics|MRSA|Tuberculosis|PCP Drug: Sulfamethoxazole/trimethoprim Texas Tech University Health Sciences Center|National Center for Research Resources (NCRR)|University of Texas Southwestern Medical Center Phase 4 2010-07-01 2016-12-21
    NCT01747278 Pneumonia, Pneumocystis|Prevention & Control Drug: Trimethoprim/Sulfamethoxazole Peking Union Medical College Hospital Phase 2|Phase 3 2012-08-01 2012-12-09
    NCT00324922 Osteomyelitis|Methicillin-resistant Staphylococcus Aureus Drug: trimethoprim-sulfamethoxazole|Drug: vancomycin University of Washington 2006-05-01 2009-07-27
    NCT02624440 Multiple Myeloma|Infection Drug: Standard myeloma treatment|Drug: Clarithromycin|Drug: Sulfamethoxazole/trimethoprim|Drug: Observation Henrik Gregersen|Danish Myeloma Study Group|Aalborg Universitetshospital Phase 2 2013-01-01 2015-12-04
    NCT03042260 Lupus Erythematosus, Systemic Drug: Trimethoprim-Sulfamethoxazole|Drug: Placebo Oral Tablet Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran|National Council of Science and Technology, Mexico Phase 4 2017-02-01 2017-02-01
    NCT00380640 Epidermolysis Bullosa Drug: Trimethoprim|Drug: Trimethoprim The Hospital for Sick Children Phase 2 2006-09-01 2013-08-01
    NCT02734732 Prostate Infection Drug: Trimethoprim/Sulfamethoxazole|Drug: Ciprofloxacin Ume氓 University Phase 2 2015-04-01 2016-04-21
    NCT00000816 Pneumonia, Pneumocystis Carinii|HIV Infections Drug: Sulfamethoxazole-Trimethoprim National Institute of Allergy and Infectious Diseases (NIAID)|Glaxo Wellcome Phase 4 null 2012-04-13
    NCT02902640 Bronchitis Drug: Guaifenesin|Drug: Sulfamethoxazole|Drug: Trimethoprim Hoffmann-La Roche 2016-11-01 2017-02-07
    NCT02371603 Anaemia Drug: GSK1278863 25 mg Tablet|Drug: Pioglitazone 15 mg Tablet|Drug: Rosuvastatin 10 mg Tablet|Drug: Trimethoprim 100 mg Tablet GlaxoSmithKline Phase 1 2015-02-01 2015-10-22
    NCT00000748 Pneumonia, Pneumocystis Carinii|HIV Infections Drug: Sulfamethoxazole-Trimethoprim National Institute of Allergy and Infectious Diseases (NIAID)|Glaxo Wellcome Phase 3 null 2013-09-28
    NCT03077711 Urinary Tract Infections, Recurrent Drug: Trimethoprim|Drug: Methenamine hippurate NorthShore University HealthSystem Phase 4 2016-06-01 2017-03-07
    NCT00189098 Chronic Otitis Media Drug: Sulfamethoxazole-trimethoprim|Drug: Placebo UMC Utrecht|Dutch Health Care Insurance Board 2003-02-01 2012-06-08
    NCT00613769 Infection Prophylaxis in Colo Rectal Surgery Drug: trimethoprim-sulfamethoxazole + metronidazole|Drug: cefuroxime and metronidazole Halmstad County Hospital Phase 4 2007-09-01 2012-09-27
    NCT00867789 Abscess Drug: Trimethoprim-sulfamethoxazole|Drug: Sugar pill Children's Mercy Hospital Kansas City|Blue Cross Blue Shield 2009-03-01 2011-06-21
    NCT00428818 Infection Drug: trimethoprim-sulfamethoxazole or doxycycline University of Texas Southwestern Medical Center 2005-08-01 2007-01-29
    NCT00870298 Prescribers' Drug Orders Drug: Trimethoprim/Sulfamethoxazole and Warfarin University of Pennsylvania 2006-08-01 2015-12-07
    NCT02475876 Bacterial Infections Drug: Clindamycin|Drug: trimethoprim-sulfamethoxazole Michael Cohen-Wolkowiez|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|Duke University Phase 1 2015-11-01 2016-08-01
    NCT02188472 Oxidative Stress Drug: Penicillin V|Drug: Trimethoprim|Drug: Placebo Henrik Enghusen Poulsen|Klinisk Biokemisk Afdeling|Klinisk farmakologisk Afdeling|Sektion for Biomedicin Institut for Veterin忙r Patobiologi|Rigshospitalet, Denmark Phase 1 2010-11-01 2014-07-09

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 ：
  • 收件地址 ：
  • 电话号码 ：
  • 单位名称 ：
  • 产品货号 ：
  • 产品规格 ：
  • 发票抬头以及单位税号 ：