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Prednisone

泼尼松,脱氢可的松,Deltasone,1-Cortisone,Dehydrocortisone

Prednisone是皮质类固醇试剂，有免疫抑制作用。

目录号
EY0589
EY0589
EY0589
纯度
99.53%
99.53%
99.53%
规格
100 mg
500 mg
1 g
原价
120
240
390
售价
120
240
390
库存
现货
现货
现货
订购
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  • 生物活性

    Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Lanza L, et al. Clin Exp Immunol, 1996, 103(3), 482-490.
    [2] Wild GE, Waschke KA, Bitton A, Thomson AB. Aliment Pharmacol Ther. 18:309-17 (2003).

    分子式
    C21H26O5    		 分子量
    358.43    		 CAS号
    53-03-2    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    70 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02534402 Chronic Obstructive Pulmonary Disease Drug: Prednisone University of British Columbia Phase 4 2015-08-01 2016-10-31
    NCT02689960 Adrenal Insufficiency Drug: 100mg prednisone suppository Wuerzburg University Hospital Phase 2 2016-04-01 2016-02-24
    NCT01933724 Granulomatosis With Polyangiitis|Wegener Granulomatosis|Vasculitis Drug: 5 mg prednisone|Drug: 0 mg prednisone University of South Florida|National Institutes of Health (NIH)|National Heart, Lung, and Blood Institute (NHLBI)|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)|Office of Rare Diseases (ORD)|National Center for Advancing Translational Science (NCATS)|Rare Diseases Clinical Research Network 2014-02-01 2016-10-24
    NCT00294658 Myasthenia Gravis Procedure: thymectomy plus prednisone|Drug: prednisone alone University of Alabama at Birmingham|National Institute of Neurological Disorders and Stroke (NINDS) Phase 3 2006-06-01 2017-01-19
    NCT01821040 Polymyalgia Rheumatica Drug: Lodotra庐|Drug: Prednisone IR (immediate release) Mundipharma Research Limited Phase 3 2013-03-01 2015-04-09
    NCT02479490 Metastatic Renal Cancer Drug: Prednisone + Everolimus Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Phase 2 2015-09-01 2016-09-28
    NCT00580229 Rheumatoid Arthritis Drug: prednisone University of South Florida Phase 2|Phase 3 2007-12-01 2016-08-10
    NCT01940094 Granulomatosis With Polyangiitis Drug: Prednisone 5 mg/day|Drug: Prednisone 0 mg/day University of Pennsylvania|National Heart, Lung, and Blood Institute (NHLBI)|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)|Office of Rare Diseases (ORD)|National Center for Advancing Translational Science (NCATS)|Rare Diseases Clinical Research Network Phase 3 2014-02-01 2017-02-21
    NCT02702778 Polymyalgia Rheumatica Drug: Delayed-Release (DR) Prednisone|Drug: Immediate Release (IR) Prednisone Dinora, Inc.|Analgesic Solutions|PharPoint Research, Inc. Phase 4 2016-02-01 2016-03-03
    NCT01452100 Cholesterol Embolism Systemic Drug: prednisone|Other: placebo University Hospital, Toulouse|Ministry of Health, France Phase 2 2011-06-01 2016-05-06
    NCT01758120 IgA Nephropathy Drug: prednisone plus cyclophosphamide|Drug: Prednisone alone Guangdong General Hospital Phase 4 2012-12-01 2017-01-17
    NCT01559727 Heart Failure Drug: prednisone|Drug: prednisone|Drug: prednisone Hebei Medical University Phase 3 2012-03-01 2013-08-27
    NCT01809444 Thyroid Associated Opthalmopathies Drug: Prednisone+placebo of Doxycycline|Drug: Doxycycline+placebo of Prednisone Sun Yat-sen University Phase 2|Phase 3 2012-11-01 2013-12-07
    NCT01002703 Multiple Myeloma Drug: Lenalidomide, Bendamustine, Prednisone University of Leipzig|Celgene Corporation|Mundipharma Pte Ltd.|Amgen Phase 1|Phase 2 2009-09-01 2011-08-11
    NCT00686335 Asthma Drug: Lodotra|Drug: Cortancyl Horizon Pharma Ireland, Ltd., Dublin Ireland Phase 2 2008-06-01 2012-11-27
    NCT01671423 Cellulitis Drug: Prednisone|Drug: Placebo Albert Einstein Healthcare Network 2012-08-01 2015-01-30
    NCT01133275 Myelodysplastic Syndrome|MDS Drug: Prednisone|Drug: Lenalidomide H. Lee Moffitt Cancer Center and Research Institute|Celgene Corporation Phase 2 2010-04-01 2016-10-25
    NCT00110669 Duchenne Muscular Dystrophy Drug: Prednisone Cooperative International Neuromuscular Research Group Phase 3 2004-01-01 2011-10-26
    NCT02282683 Heart Failure|Hyperuricemia Drug: prednisone Hebei Medical University Phase 2|Phase 3 2013-12-01 2017-01-11

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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