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Ribavirin

利巴韦林,病毒唑,三氮唑核苷,NSC 163039,NSC163039,NSC-163039,ICN-1229,ICN 1229,ICN1229,RTCA,Tribavirin,Copegus,Rebetol,Ribasphere,Vilona,Virazole

Ribavirin是一种抗病毒剂，用于治疗重症RSV感染，丙型肝炎病毒感染及其他病毒感染。

目录号
EY0500
EY0500
EY0500
纯度
99.55%
99.55%
99.55%
规格
100 mg
200 mg
500 mg
原价
460
790
1200
售价
460
790
1200
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
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  • 生物活性

    Ribavirin, a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Feld JJ, et al. Nature, 2005, 436(7053), 967-972.
    [2] Li, W., et al. 1999. Oncol. Res. 11, 243. Honda, Y., et al. 1994.

    分子式
    C8H12N4O5    		 分子量
    244.21    		 CAS号
    36791-04-5    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    49 mg/mL    		 Water
    20 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT01268579 HEAD & NECK Cancer Drug: ribavirin Memorial Sloan Kettering Cancer Center 2010-12-01 2017-01-04
    NCT00868946 Hemorrhagic Fever With Renal Syndrome Drug: Virazole (Ribavirin) U.S. Army Medical Research and Materiel Command Phase 2 2009-10-01 2016-10-11
    NCT01056757 Metastatic Breast Cancer Drug: Ribavirin Jewish General Hospital Phase 1|Phase 2 2009-12-01 2015-11-03
    NCT01097395 Hepatitis C Virus Drug: ribavirin University of Colorado, Denver|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2010-02-01 2015-08-06
    NCT01289496 Chronic Hepatitis C Drug: Peg-interferon alpha-2a, Ribavirin Centre hospitalier de l'Universitde Montral (CHUM)|Hoffmann-La Roche|Centre de Recherche du Centre Hospitalier de l'Universitde Montral Phase 2 2011-02-01 2014-02-24
    NCT00992693 Crimean-Congo Hemorrhagic Fever|Lassa Fever Drug: Ribavirin (Virazole) Injection U.S. Army Medical Research and Materiel Command|Valeant Pharmaceuticals International, Inc. Phase 2 2009-09-01 2016-08-24
    NCT00993122 Hepatitis C Drug: ribavirin pre-treatment University of Roma La Sapienza Phase 4 2009-10-01 2015-06-19
    NCT01056523 Acute Myeloid Leukemia Drug: Ribavirin|Drug: Cytarabine arabinoside Jewish General Hospital|The Leukemia and Lymphoma Society Phase 1|Phase 2 2010-01-01 2016-12-02
    NCT02308241 Human Papillomavirus (HPV)-Related Malignancies|Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies Drug: Ribavirin Memorial Sloan Kettering Cancer Center 2014-12-01 2016-12-20
    NCT00500578 Hematological Malignancies Drug: Ribavirin|Drug: Ribavirin M.D. Anderson Cancer Center|ICN Pharmaceuticals Phase 4 2003-02-01 2012-07-27
    NCT01309490 Malignant Solid Tumour Drug: Ribavirin Jewish General Hospital Phase 1|Phase 2 2011-03-01 2011-03-04
    NCT02716779 Hepatitis C, Chronic Drug: Pegylated Interferon (PEG-IFN) alfa-2a|Drug: Placebo|Drug: Ribavirin Hoffmann-La Roche|Roche Pharma AG Phase 2 2007-04-01 2016-07-20
    NCT00559091 Acute Myelocytic Leukemia Drug: ribavirin Jewish General Hospital|The Leukemia and Lymphoma Society Phase 2 2007-04-01 2011-05-06
    NCT00887081 Hemoglobinopathies Drug: PEG-IFN alpha2a or PEG-IFN alpha2b and Ribavirin Azienda Ospedaliera V. Cervello Phase 4 2009-01-01 2009-04-22
    NCT02593162 Hepatitis C Viral Infection|Chronic Hepatitis C|Hepatitis C (HCV)|Hepatitis C Genotype 4 Drug: Faldaprevir|Drug: TD-6450|Drug: Ribavirin Trek Therapeutics, PBC Phase 2 2015-10-01 2017-01-27
    NCT02261662 Hepatitis C|Lichen Planus|Vasculitis|Autoimmune Diseases Drug: Ribavirin|Drug: Betamethasone Tanta University 2014-06-01 2014-10-06
    NCT00484328 Hepatitis C Drug: Ribavirin Maastricht University Medical Center|Roche Pharma AG Phase 4 2007-07-01 2011-07-19
    NCT01006031 Liver Cirrhosis|Hepatitis C Virus|HIV Infection Drug: Pegylated interferon alfa-2a and Ribavirin Sociedad Andaluza de Enfermedades Infecciosas Phase 2|Phase 3 2009-10-01 2011-12-28
    NCT00840489 Chronic Hepatitis C Drug: Ribavirin|Drug: Colchicine Hospital Universitario Ramon y Cajal Phase 2 2009-01-01 2013-01-30
    NCT00725751 Hepatitis C, Chronic Biological: Pegylated interferon alfa-2b (PegIFN-2b)|Drug: Ribavirin Merck Sharp & Dohme Corp. 2007-09-01 2015-10-01
    NCT01098097 Hepatitis C, Chronic Biological: Peginterferon alpha|Drug: Ribavirin Merck Sharp & Dohme Corp. 2009-06-01 2014-11-14
    NCT01726400 Hepatitis C Drug: Pegylated interferon alpha|Drug: Ribavirin Fremantle Hospital and Health Service 2012-12-01 2015-11-09
    NCT00982553 HIV Infections Drug: Ribavirin|Drug: Raltegravir Imperial College London Phase 1 2009-09-01 2011-11-04
    NCT00192647 Hepatitis C, Chronic Drug: PEG-IFN alfa-2a|Drug: Ribavirin Hoffmann-La Roche Phase 4 2004-08-01 2016-06-23

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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