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Miglitol

米格列醇,BAY-M-1099,Glyset,Seibule,Diastabol,BAY1099

Miglitol是口服的抗糖尿病化合物,能抑制糖复合体分解为葡萄糖。

目录号
EY0477
EY0477
EY0477
EY0477
纯度
99.33%
99.33%
99.33%
99.33%
规格
100 mg
500 mg
1 g
5 g
原价
150
340
540
1420
售价
150
340
540
1420
库存
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Miglitol is an oral anti-diabetic drug.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Lembcke, B., et al.: Digestion, 31, 120 (1985)
    [2] Yoshikuni, Y., et al.: J. Pharmacobio-Dyn., 11, 356 (1988)

    分子式
    C8H17NO5
    分子量
    207.22
    CAS号
    72432-03-2
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    3 mg/mL
    Water
    <1 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT01099839 Healthy Volunteers|Pharmacokinetics of ASP1941 Drug: ASP1941|Drug: Miglitol Astellas Pharma Inc Phase 1 2010-02-01 2010-06-08
    NCT00213122 Type 2 Diabetes Mellitus Drug: miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2006-09-25
    NCT00380822 Type 2 Diabetes Mellitus Drug: miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2006-09-25
    NCT00213109 Type 1 Diabetes Mellitus Drug: Miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2006-09-20
    NCT00334503 Type 2 Diabetes Mellitus Drug: Miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2008-10-08
    NCT00213070 Type 2 Diabetes Mellitus Drug: Miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2006-09-20
    NCT00334399 Type 2 Diabetes Mellitus Drug: Miglitol Sanwa Kagaku Kenkyusho Co., Ltd. Phase 3 null 2008-10-08
    NCT01242202 Type 2 Diabetes Mellitus Drug: ASP1941|Drug: alpha glucosidase inhibitor Astellas Pharma Inc Phase 3 2010-10-01 2016-01-18
    NCT02669693 Diabetes Dietary Supplement: bread without olives|Dietary Supplement: bread with olives University of Leeds 2015-12-01 2017-03-22
    NCT01697592 Type 2 Diabetes Mellitus Drug: Omarigliptin|Drug: Matching placebo to omarigliptin Merck Sharp & Dohme Corp. Phase 3 2012-10-01 2016-10-28
    NCT02475499 Diabetes Mellitus, Type 2 Drug: DPP-4 inhibitors|Drug: GLP-1 analogs|Drug: Sulfonylureas|Drug: Biguanides|Drug: Thiazolidinediones|Drug: Alpha-glucosidase inhibitors|Drug: Meglitinides Canadian Network for Observational Drug Effect Studies, CNODES|Drug Safety and Effectiveness Network, Canada|Canadian Institutes of Health Research (CIHR) 2014-03-01 2016-03-11
    NCT02476760 Diabetes Mellitus, Type 2 Drug: DPP-4 inhibitors|Drug: GLP-1 analogs|Drug: Insulins|Drug: Biguanides|Drug: Sulfonylureas|Drug: Thiazolidinediones|Drug: Alpha-glucosidase inhibitors|Drug: Meglitinides Canadian Network for Observational Drug Effect Studies, CNODES|Drug Safety and Effectiveness Network, Canada|Canadian Institutes of Health Research (CIHR) 2014-03-01 2016-11-01
    NCT02456428 Type 2 Diabetes Mellitus Drug: DPP-4 inhibitors|Drug: GLP-1 analogs|Drug: Insulins|Drug: Biguanides|Drug: Sulfonylureas|Drug: Thiazolidinediones|Drug: Alpha-glucosidase inhibitors|Drug: Meglitinides Canadian Network for Observational Drug Effect Studies, CNODES|Drug Safety and Effectiveness Network, Canada|Canadian Institutes of Health Research (CIHR) 2014-03-01 2016-04-15

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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