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Fluocinolone Acetonide

醋酸肤轻松,醋酸氟轻松,Flucort-N

Fluocinolone Acetonide是糖皮质激素衍生物，可作用于各种皮肤病。

目录号
EY0434
EY0434
纯度
99.17%
99.17%
规格
100 mg
500 mg
原价
360
585
售价
360
585
库存
现货
现货
订购
订购
订购
订购
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  • 生物活性

    Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Nehmé, A., et al. 2009. BMC Med Genomics. 2: 58. PMID: 19744340
    [2] Thongprasom, K., et al. 2006. J. Oral Pathol. Med. 35: 161-166. PMID: 16454812
    [3] Ayalasomayajula, S.P., et al. 2009. J Ocul Pharmacol Ther. 25: 97-103. PMID: 19284324

    分子式
    C24H30F2O6    		 分子量
    452.5    		 CAS号
    67-73-2    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    90 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    12 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT00543296 Uveitis Drug: 0.59 mg Fluocinolone Acetonide implant Duke University|Bausch & Lomb Incorporated Phase 4 2004-03-01 2015-03-12
    NCT01781936 Uveitis Affecting the Posterior Segment. Drug: Fluocinolone Acetonide Glenn Jaffe|Duke University Phase 1 2012-06-01 2016-04-05
    NCT01060787 Inflammation|Uveitis Procedure: Fluocinolone Acetonide 0.59 mg|Procedure: Fluocinolone Acetonide 2.1 mg Bausch & Lomb Incorporated 2006-08-01 2017-02-08
    NCT00636493 Retinal Vein Occlusion Device: fluocinolone acetonide (Retisert Implant) Glenn Jaffe|Bausch & Lomb Incorporated|Duke University Early Phase 1 2002-10-01 2012-12-11
    NCT02359526 Diabetic Macular Edema Drug: IlUVIEN Association for Innovation and Biomedical Research on Light and Image Phase 4 2014-10-01 2017-03-09
    NCT00456482 Non-infectious Uveitis Drug: Fluocinolone Acetonide 0.59mg|Drug: Fluocinolone Acetonide 2.1mg Bausch & Lomb Incorporated Phase 2|Phase 3 2002-05-01 2011-12-07
    NCT00407082 Noninfectious Posterior Uveitis Drug: fluocinolone acetonide intravitreal implant|Drug: Fluocinolone acetonide 2.1mg Bausch & Lomb Incorporated Phase 2|Phase 3 2000-12-01 2011-12-07
    NCT00490815 Diabetic Macular Edema Drug: Fluocinolone Acetonide|Drug: Fluocinolone Acetonide Alimera Sciences Phase 3 2007-08-01 2014-01-17
    NCT02424019 Diabetic Macular Edema (DME) Drug: ILUVIEN庐 Alimera Sciences Phase 4 2015-04-01 2017-01-05
    NCT00952614 Central Retinal Vein Occlusion Device: fluocinolone acetonide (Retisert Implant, Bausch and Lomb) Glenn Jaffe|Bausch & Lomb Incorporated|Duke University 2002-10-01 2014-08-01
    NCT00502541 Diabetic Macular Edema Drug: fluocinolone acetonide|Procedure: Standard of Care Bausch & Lomb Incorporated Phase 2|Phase 3 2001-09-01 2013-11-27
    NCT00468871 Non-infectious Uveitis Drug: fluocinolone acetonide intravitreal implant|Drug: corticosteroids and immunosuppressants Bausch & Lomb Incorporated Phase 2|Phase 3 2002-04-01 2011-12-07
    NCT00576459 Diabetic Macular Edema Drug: 0.59 mg fluocinolone acetonide intravitreal implant|Drug: 2.1 mg fluocinolone acetonide intravitreal implant|Procedure: standard of care laser photocoagulation Bausch & Lomb Incorporated Phase 2 2003-03-01 2011-12-07
    NCT00344968 Diabetic Macular Edema Drug: fluocinolone acetonide|Drug: Fluocinolone Acetonide|Procedure: Standard of care laser photocoagulation Alimera Sciences Phase 3 2007-09-01 2014-04-08
    NCT00570830 Intermediate Uveitis|Posterior Uveitis Device: Retisert (fluocinolone acetonide implant) Duke University 2006-09-01 2014-08-29
    NCT02902744 Diabetic Macular Edema Drug: ILUVIEN庐 Johns Hopkins University Phase 4 2016-09-01 2016-09-12
    NCT00770770 Macular Edema|Retinal Vein Occlusion Drug: Fluocinolone Acetonide|Drug: Fluocinolone Acetonide Alimera Sciences Phase 2 2009-05-01 2015-05-08
    NCT00605423 Age Related Macular Degeneration Drug: Fluocinolone Acetonide/Medidur|Drug: Fluocinolone Acetonide/Medidur Johns Hopkins University|Alimera Sciences|pSiVida Limited Phase 2 2008-01-01 2014-03-10
    NCT01304706 Diabetic Macular Edema Drug: Fluocinolone Acetonide Alimera Sciences Phase 3 2011-04-01 2015-04-17
    NCT00695318 Age-Related Macular Degeneration Drug: Fluocinolone Acetonide|Drug: Fluocinolone Acetonide Alimera Sciences Phase 2 2008-12-01 2015-05-11

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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