Dexmedetomidine

右美托咪定

Dexmedetomidine是特护病房和麻醉师使用的一种镇静剂。

目录号
EY0432
EY0432
EY0432
纯度
99.17%
99.17%
99.17%
规格
25 mg
50 mg
100 mg
原价
478
778
1200
售价
478
778
1200
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Virtanen R, et al. Eur J Pharmacol, 1988, 150(1-2), 9-14.

    分子式
    C13H16N2
    分子量
    200.28
    CAS号
    113775-47-6
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    50 mg/mL
    Water
    50 mg/mL
    Ethanol
    50 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT01498380 Hemodynamic Instability Drug: Dexmedetomidine University of British Columbia 2012-01-01 2014-02-05
    NCT02327156 Vitreoretinal Surgery Under Sub-Tenon's Anesthesia Drug: dexmedetomidine Magrabi Eye & Ear Hospital Phase 3 2014-01-01 2014-12-29
    NCT02566863 Haemodynamic Effects of Dexmedetomidine Drug: Dexmedetomidine Medical University of Gdansk Phase 4 2015-06-01 2017-03-21
    NCT02187068 Obesity Drug: Dexmedetomidine Pontificia Universidad Catolica de Chile Phase 4 2012-04-01 2014-07-07
    NCT02715154 Cesarean Section, Affecting Fetus or Newborn Drug: Dexmedetomidine|Drug: Placebo The First Affiliated Hospital with Nanjing Medical University Phase 1 2015-06-01 2016-03-21
    NCT02108171 Benign Neoplasm of Vocal Fold - Glottis Drug: Dexmedetomidine|Drug: placebo Guangzhou First Municipal People鈥檚 Hospital 2014-03-01 2016-02-13
    NCT01485380 Dexmedetomidine Induced Sedation Drug: dexmedetomidine Massachusetts General Hospital 2012-09-01 2016-06-20
    NCT01900405 Traumatic Brain Injury|Children Drug: Dexmedetomidine University of Sao Paulo|Boston Children鈥檚 Hospital 2013-04-01 2013-07-11
    NCT02557867 Obesity Drug: Dexmedetomidine Pontificia Universidad Catolica de Chile Phase 4 2015-08-01 2016-10-10
    NCT02529202 Hypoxic-ischemic Encephalopathy Drug: Dexmedetomidine Seattle Children's Hospital Early Phase 1 2016-03-01 2017-01-10
    NCT01976754 Sepsis|Agitation Drug: Dexmedetomidine First Affiliated Hospital of Zhejiang University 2013-09-01 2013-10-30
    NCT01864187 Obesity Drug: Dexmedetomidine Guangzhou General Hospital of Guangzhou Military Command Phase 4 2013-06-01 2015-03-11
    NCT00345384 Post-operative Pain|Respiratory Depression Drug: Dexmedetomidine|Other: Placebo (Normal Saline) Baylor Research Institute Phase 1|Phase 2 2008-05-01 2016-01-12
    NCT02155010 Blood Pressure|Anxiety Drug: Dexmedetomidine|Drug: Dexmedetomidine with heavy bupivacaine Inje University 2014-03-01 2016-08-03
    NCT00573066 Hypoplastic Left Heart|Tetralogy of Fallot|Tricuspid Atresia Drug: Dexmedetomidine Athena Zuppa|Children's Hospital of Philadelphia Phase 1 2004-05-01 2013-02-28
    NCT01116700 Seizure Disorders Drug: Dexmedetomidine University of California, San Francisco Phase 1 2010-12-01 2013-08-06
    NCT02299232 Anesthesia Drug: Dexmedetomidine Sisli Etfal Training & Research Hospital Phase 4 2014-02-01 2014-11-19
    NCT01920542 Acute Renal Injury Drug: Dexmedetomidine|Drug: no dexmedetomidine Gachon University Gil Medical Center 2013-09-01 2016-11-08
    NCT00837187 Sedation Drug: Intravenous dexmedetomidine|Drug: Intranasal dexmedetomidine University of Turku Phase 1 2009-03-01 2010-01-12
    NCT02459509 Anxiety, Separation Drug: Dexmedetomidine The University of Hong Kong Phase 4 2015-06-01 2016-04-15
    NCT00576381 Tetrology of Fallot|Heart Ventricle|Hypoplastic Left Heart Drug: Dexmedetomidine Athena Zuppa|Children's Hospital of Philadelphia Phase 1 2006-04-01 2013-04-10
    NCT01887184 Gastrointestinal Disease Drug: Dexmedetomidine The University of Hong Kong Phase 3 2009-01-01 2014-10-24
    NCT02757495 Delayed Emergence From Anesthesia Drug: Dexmedetomidine Suez Canal University Phase 4 2016-04-01 2016-05-03
    NCT02004613 Heart Disease Drug: Dexmedetomidine|Drug: Placebo The Cleveland Clinic|Hospira, Inc. Phase 4 2013-06-01 2017-02-03
    NCT00455143 Postoperative Delirium|PD|Postoperative Cognitive Dysfunction|POCD Drug: Precedex (Dexmedetomidine) Icahn School of Medicine at Mount Sinai Phase 4 2006-09-01 2016-03-16

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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