Home > Estrogen/progestogen Receptor & > Ulipristal

Ulipristal

乌利司他,CDB-2914,CDB 2914,CDB2914

Ulipristal是一种选择性的孕酮受体调节剂(SPRM)，用于无保护措施性交或避孕失败后的紧急避孕。

目录号
EY0414
EY0414
EY0414
纯度
99.21%
99.21%
99.21%
规格
5 mg
10 mg
50 mg
原价
890
1320
4250
售价
890
1320
4250
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
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  • 生物活性

    Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Attardi BJ, et al. J Steroid Biochem Mol Biol, 2004, 88(3), 277-288.

    分子式
    C30H37NO4    		 分子量
    475.62    		 CAS号
    159811-51-5    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    80 mg/mL    		 Water
    <1 mg/mL    		 Ethanol
    12 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT02213081 Endometriosis Drug: Ulipristal Northwestern University Phase 4 2015-02-01 2016-09-27
    NCT02517463 Contraception Drug: Ulipristal acetate The University of Hong Kong|The Family Planning Association of Hong Kong 2011-05-01 2015-08-04
    NCT02922127 Contraception Drug: Ulipristal Acetate|Drug: Combined Oral Contraceptive Pill Columbia University|Weill Medical College of Cornell University|Memorial Sloan Kettering Cancer Center Phase 1 2016-12-16 2017-02-06
    NCT02634437 Renal Function Drug: Ulipristal acetate Forest Laboratories Phase 1 2015-12-01 2016-09-07
    NCT02601196 Women With Leiomyoma After at Least One Unsuccessful IVF Treatment Drug: Ulipristal acetate Sheba Medical Center Phase 4 2016-09-01 2016-07-10
    NCT02361905 Fibroid Drug: ulipristal acetate|Drug: Leuprolide acetate University Magna Graecia Phase 4 2015-02-01 2016-11-17
    NCT01391845 Infertility Drug: ulipristal acetate|Drug: placebo|Drug: ulipristal acetate|Drug: placebo Programa de Asistencia Reproductiva de Rosario 2011-07-01 2011-07-19
    NCT02361879 Fibroid Drug: ulipristal acetate|Drug: Leuprolide acetate University Magna Graecia Phase 4 2015-02-01 2016-11-17
    NCT02451826 Ovulation Inhibition Drug: Ulipristal acetate Population Council Phase 1|Phase 2 2015-05-01 2016-05-27
    NCT02825719 Fibroid Drug: Ulipristal acetate|Other: Placebo pills|Drug: Ferrous sulphate|Drug: Tranexamic Acid Queen Mary Hospital, Hong Kong Phase 4 2015-11-01 2017-01-30
    NCT00290251 Leiomyoma Drug: ulipristal acetate|Drug: ulipristal acetate|Drug: placebo Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|HRA Pharma|National Institutes of Health Clinical Center (CC) Phase 2 2006-02-01 2012-11-14
    NCT02587000 Adenomyosis Drug: Ulipristal acetate|Drug: Placebo Assistance Publique - H么pitaux de Paris|Gedeon Richter Ltd. Phase 2 2015-05-01 2017-03-21
    NCT02288130 Fibroids Drug: GnRHa|Drug: Ulipristal VU University Medical Center Phase 4 2014-12-01 2016-11-02
    NCT02357563 Fibroid Drug: ulipristal acetate|Drug: Leuprolide acetate University Magna Graecia Phase 4 2015-02-01 2016-11-17
    NCT01953679 Focus: Estrogen-free Oral Contraception Drug: Ulipristal Acetate Health Decisions|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Phase 2 2014-03-01 2016-02-19
    NCT02147197 Uterine Bleeding in Women With Leiomyomas Drug: Ulipristal acetate 5 mg|Drug: Ulipristal acetate 10 mg|Drug: Placebo Watson Pharmaceuticals Phase 3 2014-04-01 2017-03-16
    NCT01642472 Uterine Fibroids Drug: Ulipristal Acetate - open label PregLem SA Phase 3 2012-07-01 2016-01-07
    NCT01553123 Leiomyomas Drug: Ulipristal Acetate|Drug: Iron Watson Pharmaceuticals Phase 3 2012-04-01 2013-02-05
    NCT01569737 Emergency Contraception Drug: ella HRA Pharma 2012-01-01 2014-09-18
    NCT02361892 Infertility Drug: ulipristal acetate University Magna Graecia Phase 4 2015-02-01 2016-11-17

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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