Oxibendazole是广谱的驱虫剂。
Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] F F Franssen et. Al. Antimicrobial Agents and Chemotherapy, 39(6), 1265-1268 (1995).
[2] Nigel Greene et. Al. Chemical Research in Toxicology, 23(7), 1215-1222 (2010).
[3] Sean Ekins et. Al. Drug Metabolism and Disposition, 38(12), 2302-2308 (2010).
分子式 C12H15N3O3 |
分子量 249.27 |
CAS号 20559-55-1 |
储存方式 ﹣20 ℃冷藏长期储存。冰袋运输 |
溶剂(常温) |
DMSO 1 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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