Azithromycin

阿奇霉素,阿泽红霉素,阿齐霉素,CP 62993,CP62993,CP-62993,XZ-450,XZ450,XZ 450

Azithromycin是抑制寄生虫类抗生素,IC50为8.4 μM。

目录号
EY0334
EY0334
EY0334
纯度
99.24%
99.24%
99.24%
规格
25 mg
50 mg
100 mg
原价
430.00
780
1100
售价
430.00
780
1100
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Saint-Criq, V., et al. 2011. Antimicrob Agents Chemother. [Epub ahead of print]. PMID: 21220528
    [2] Kumar, A.P. and Park, J.H. 2011. J Chromatogr A. 1218: 1314-1317. PMID: 21256503
    [3] Cigana, C., et al. 2007. Antimicrob. Agents Chemother. 51: 975-981. PMID: 17210769
    [4] Mabe, S., et al. 2004. Curr. Microbiol. 49: 248-254. PMID: 15386112

    分子式
    C38H72N2O12
    分子量
    748.98
    CAS号
    83905-01-5
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    102 mg/mL
    Water
    <1 mg/mL
    Ethanol
    100 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT00879983 Healthy Volunteers Drug: azithromycin (Zithromax)|Drug: azithromycin (Zithromax) Pfizer Phase 1 2009-05-01 2010-06-11
    NCT01109160 Lymphocytic Bronchi(Oli)Tis Post-lung Transplantation Drug: Azithromycin Dihydrate Katholieke Universiteit Leuven|Fund for Scientific Research, Flanders, Belgium Phase 4 2010-04-01 2013-07-03
    NCT02307825 Chronic Rhinosinusitis|High-risk Patient Drug: Azithromycin|Drug: Placebo Centre hospitalier de l'Universit茅 de Montr茅al (CHUM)|Pfizer Phase 4 2014-11-01 2016-09-26
    NCT02911935 Respiratory Syncytial Virus, Bronchiolitis Drug: Oral azithromycin|Drug: Placebo Washington University School of Medicine Phase 2|Phase 3 2016-11-01 2016-11-05
    NCT02575755 Pregnancy|Infections, Plasmodia|Drug Kinetics|Clinical Efficacy Drug: Azithromycin plus piperaquine phosphate|Drug: Sulfadoxine-pyrimethamine Papua New Guinea Institute of Medical Research|The University of Western Australia|University of Melbourne|Malaria in Pregnancy Consortium Phase 4 2012-10-01 2015-10-14
    NCT02196493 Chronic Cough Drug: Azithromycin University of Nottingham Phase 3 2013-12-01 2016-02-17
    NCT01009619 Bronchiolitis Obliterans Syndrome|Graft Rejection|Lymphocytic Bronchiolitis|Respiratory Infection Drug: Azithromycin|Drug: Placebo Katholieke Universiteit Leuven|University Hospital, Gasthuisberg|Fund for Scientific Research, Flanders, Belgium Phase 4 2005-09-01 2011-08-29
    NCT01178762 Chlamydial Conjunctivitis Drug: Azithromycin National Taiwan University Hospital 2007-09-01 2010-10-05
    NCT01008761 Asthma Drug: Azithromycin|Drug: Suspension Placebo Janielee Williamson|University of Alberta|Alberta Children's Hospital 2010-01-01 2012-07-11
    NCT03090048 Acne Vulgaris Drug: Vitamin A|Drug: Azithromycin Manchanda Medical Clinic Early Phase 1 2017-04-20 2017-03-21
    NCT00844207 Malaria Drug: Fixed combination of Azithromycin and Chloroquine|Drug: Azithromycin and Chloroquine Pfizer Phase 1 2009-02-01 2009-04-20
    NCT02926326 Interaction Drug: BCT197|Drug: Azithromycin Mereo BioPharma Phase 1 2016-09-01 2016-10-21
    NCT01783860 Posterior Blepharitis Drug: Azithromycin|Drug: Doxycycline Tehran University of Medical Sciences Phase 2 2013-01-01 2013-12-28
    NCT02107274 Bronchiectasis Drug: Azithromycin|Drug: Placebo for Azithromycin Penang Hospital, Malaysia Phase 4 2011-11-01 2014-07-09
    NCT01227395 HIV Infection Drug: Azithromycin Pfizer|Altmarc Inc. 2002-07-01 2013-04-18
    NCT00834132 Healthy Drug: Azithromycin 600 mg Tablet|Drug: Zithromax庐 600 mg Tablet Teva Pharmaceuticals USA Phase 1 2002-07-01 2009-09-11
    NCT01671280 Community-acquired Pneumonia|Pelvic Inflammatory Disease Drug: Azithromycin IV Pfizer 2012-09-01 2017-02-09
    NCT00834756 Healthy Drug: Azithromycin 600 mg Tablet|Drug: Zithromax庐 600 mg Tablet Teva Pharmaceuticals USA Phase 1 2002-09-01 2009-09-11
    NCT02803944 Cystic Fibrosis Drug: Azithromycin Hospices Civils de Lyon 2014-09-01 2016-06-14
    NCT02047981 Childhood Mortality Drug: Azithromycin|Drug: Placebo University of California, San Francisco|Bill and Melinda Gates Foundation|Johns Hopkins University|London School of Hygiene and Tropical Medicine Phase 4 2014-12-01 2016-10-12
    NCT01154569 Bariatric Surgery Drug: Azithromycin University of Alberta 2010-06-01 2011-07-28
    NCT01778634 Ureaplasma Infections Drug: Azithromycin|Drug: Placebo (for azithromycin) Rose Viscardi|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|Mercy Medical Center|Johns Hopkins University|University of Virginia|University of Alabama at Birmingham|Christiana Care Health Services|University of Maryland Phase 2 2013-07-01 2015-05-28
    NCT01379196 Graves Ophthalmopathy Drug: Azithromycin Rabin Medical Center Phase 1|Phase 2 2011-05-01 2011-06-22

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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