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Vitamin C

维生素C,抗坏血酸,Ascorbic acid

Ascorbic acid是天然有机物,有抗氧化活性。

目录号
EY0303
EY0303
EY0303
纯度
99.57%
99.57%
99.57%
规格
100 mg
500 mg
1 g
原价
140
320
430
售价
140
320
430
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Vitamin C is a water-soluble vitamin indicated for the prevention and treatment of scurvy.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Bram S, et al. Nature, 1980, 284(5757), 629-631.
    [2] Ran Kang et. Al. Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity. Stem Cell Research & Therapy, 6(1), 144 (2015).
    [3]Qingjie Wang et. Al. Soluble epoxide hydrolase is involved in the development of atherosclerosis and arterial neointima formation by regulating smooth muscle cell migration. American Journal of Physiology - Heart and Circulatory Physiology, 309(11), H1894-H1903 (2015).

    分子式
    C6H8O6
    分子量
    176.12
    CAS号
    50-81-7
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    20 mg/mL
    Water
    10 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT02606773 Vitamin C Deficiency Drug: Ascorbic Acid Semmelweis University|Novonex Pharma Kft Phase 1 2015-06-01 2015-11-16
    NCT02083575 Vitamin c|Thalassemia Major|Iron Chelation Drug: Vitamin C, Defriprone, deferisarox|Drug: deferiprone , deferesarox Ain Shams University Phase 2|Phase 3 2014-04-01 2014-03-07
    NCT01723696 Pulmonary Function; Newborn, Abnormal|Infant Wheeze|In-utero Nicotine|Second Hand Smoke Dietary Supplement: Vitamin C +prenatal vitamin|Dietary Supplement: Placebo tablet+prenatal vitamin Oregon Health and Science University|National Heart, Lung, and Blood Institute (NHLBI)|Office of Dietary Supplements (ODS) Phase 2|Phase 3 2012-12-01 2016-09-26
    NCT01356433 Uremia|Inflammation Drug: oral vitamin C|Drug: oral vitamin C Peking University First Hospital Phase 4 2011-08-01 2012-09-19
    NCT01743742 Birth Asphyxia Drug: Vitamin E, Vitamin C Sir Takhtasinhji General Hospital Phase 4 2013-05-01 2014-08-22
    NCT02780505 Anemia Drug: vitamin c|Drug: placebo Shiraz University of Medical Sciences Phase 4 2011-11-01 2016-05-19
    NCT00350077 Burns Drug: Intravenous Vitamin C|Drug: Vitamin C United States Army Institute of Surgical Research|University of Miami 2006-07-01 2011-12-19
    NCT01369043 Exercise and Non-exercise Effect Upon Vitamins E and C Dietary Supplement: Vitamin E and Vitamin C USDA Grand Forks Human Nutrition Research Center 2011-05-01 2015-03-06
    NCT01413360 Chronic Hepatitis|Chronic Hepatitis C|Chronic Alcoholic Hepatitis Drug: High dose vitamin C Seoul National University Hospital Phase 4 2011-08-01 2016-06-06
    NCT02455180 Multiple Organ Failure|Sepsis|Systemic Inflammatory Response Syndrome|Trauma Drug: Ascorbic Acid VU University Medical Center Phase 4 2015-03-01 2016-05-09
    NCT02369822 Idiopathic Epilepsy Dietary Supplement: Vitamin C Ain Shams University Phase 2 2015-02-01 2015-02-23
    NCT00534014 Atherosclerosis|Type 2 Diabetes Dietary Supplement: Vitamin C University of New Mexico|American Diabetes Association 2006-01-01 2008-03-31
    NCT02762331 Disorder of Vitamin C|Atrial Fibrillation|Complications Due to Coronary Artery Bypass Graft|Heart Valve Disease Drug: Ascorbic Acid|Drug: Placebo Virginia Commonwealth University Phase 1 2017-01-01 2017-03-02
    NCT01587261 Severe Thermal Injury, Greater Than 20% TBSA Drug: Vitamin C|Drug: Placebo University of Texas Southwestern Medical Center Phase 2 2017-06-01 2016-01-12
    NCT01090895 Angina Pectoris Drug: Vitamin C|Drug: Placebo University of Roma La Sapienza Phase 4 2010-03-01 2016-03-08
    NCT01338129 Ankle Fracture Dietary Supplement: vitamin c|Drug: placebo Rabin Medical Center 2011-04-01 2011-04-18
    NCT00920413 Anemia|Peritoneal Dialysis Dietary Supplement: Vitamin C|Dietary Supplement: placebo St. Michael's Hospital, Toronto Phase 3 2002-03-01 2009-06-12
    NCT00869427 Urinary Tract Infection|Spinal Cord Injury Drug: vitamin C Sunnaas Rehabilitation Hospital|Dentsply Sirona Implants Phase 4 2009-03-01 2010-07-02
    NCT01434121 Sepsis|Septic Shock|Hypotension|Acute Lung Injury Drug: Ascorbic Acid|Drug: Placebo Virginia Commonwealth University Phase 1|Phase 2 2010-05-01 2014-05-30
    NCT01319734 Type 2 Diabetes Mellitus Dietary Supplement: Vitamin C|Drug: glyburide Al-Neelain University Phase 1 2011-02-01 2013-09-17

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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