Clomifene citrate (Serophene) is a selective estrogen receptor modulator.
Clomifene citrate (Serophene) is a selective estrogen receptor modulator.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] E. Moll,et al. Does adding metformin to clomifene citrate lead to higher pregnancy rates in a subset of women with polycystic ovary syndrome? Hum Reprod. 2008 Aug; 23(8): 1830–1834. Published online 2008 May 17. doi: 10.1093/humrep/den182.
[2] Etelka Moll,et al. Effect of clomifene citrate plus metformin and clomifene citrate plus placebo on induction of ovulation in women with newly diagnosed polycystic ovary syndrome: randomised double blind clinical trial. BMJ. 2006 Jun 24; 332(7556): 1485. doi: 10.1136/bmj.38867.631551.55.
分子式 C32H36ClNO8 |
分子量 598.08 |
CAS号 50-41-9 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 120 mg/mL |
Water <1 mg/mL |
Ethanol 13 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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