Netilmicin Sulfate is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria.
Netilmicin Sulfate is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin. The compound can be detected with the use of liquid chromatography. With an IC50 = 0.963 mM Netilmicin Sulfate inhibited rat erythrocyte PGD (6-phosphogluconate dehydrogenase) in vitro.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Campoli-Richards, D.M., et al. 1989. Drugs. 38: 703-756.
[2] Ciftçi, M., et al. 2002. Pol J Pharmacol. 54: 275-280.
[3] Adams, E., et al. 1998. J Chromatogr A. 812: 151-157.
分子式 C42H92N10O34S5 |
分子量 1441.55 |
CAS号 56391-57-2 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO <1 mg/mL |
Water 300 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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