Diflunisal is a NSAID analgesic with an unusually long duration of action. Diflunisal has been found to exhibit anti-proliferative effects against colon adenocarcinoma cells.
Diflunisal is a NSAID analgesic with an unusually long duration of action. Diflunisal has been found to exhibit anti-proliferative effects against colon adenocarcinoma cells.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Forbes, J.A., et al. 1982. JAMA. 248: 2139-2142.
[2] Cannell, G.R., et al. 2001. Life. Sci. 70: 37-48.
分子式 C13H8F2O3 |
分子量 250.20 |
CAS号 22494-42-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 60 mg/mL |
Water <1 mg/mL |
Ethanol 28 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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