Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. Tyloxapol is employed as a surfactant in bronchopulmonary studies of liquefaction and removal of mucupurulent secretions.
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. Tyloxapol is employed as a surfactant in bronchopulmonary studies of liquefaction and removal of mucupurulent secretions.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Kristl J, et al. Toxicol Appl Pharmacol. 2008, 232(2):218-225.
[2] Zheng J, et al. Chem Pharm Bull (Tokyo). 2010, 58(12):161
分子式 C51H80O6R5 |
分子量 789.18 |
CAS号 25301-02-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO ≥30 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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