Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Azza S. Zakaria,et al. Biomed Res Int. 2016; 2016: 6525163. Published online 2016 May 24. doi: 10.1155/2016/6525163.
[2] Sook Wah Yee,et al. J Pharm Sci. Author manuscript; available in PMC 2014 Sep 2. Published in final edited form as: J Pharm Sci. 2013 Sep; 102(9): 3451–3457. Published online 2013 May 6. doi: 10.1002/jps.23581.
分子式 C16H16N5NaO7S2 |
分子量 477.45 |
CAS号 64485-93-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO >90 mg/mL |
Water >90 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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