Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.
Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Seeta Poudel, Youngseok Lee. Mol Cells. 2016 Apr 30; 39(4): 310–315. Published online 2016 Feb 25. doi: 10.14348/molcells.2016.2250.
[2] E Danese,et al. Clin Pharmacol Ther. Author manuscript; available in PMC 2013 Dec 1. Published in final edited form as: Clin Pharmacol Ther. 2012 Dec; 92(6): 746–756. Published online 2012 Nov 7. doi: 10.1038/clpt.2012.184.
分子式 C9H6O2 |
分子量 146.14 |
CAS号 91-64-5 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 33 mg/mL |
Water <1 mg/mL |
Ethanol 33 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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