Methenamine is an antibiotic used for the treatment of urinary tract infection.
Methenamine is an antibiotic used for the treatment of urinary tract infection.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] S Cronberg,et al. Prevention of recurrent acute cystitis by methenamine hippurate: double blind controlled crossover long term study. Br Med J (Clin Res Ed) 1987 Jun 13; 294(6586): 1507–1508.
[2] G Davies,et al. The reversible cerebral vasoconstriction syndrome in association with venlafaxine and methenamine. BMJ Case Rep. 2013; 2013: bcr2013009701. Published online 2013 Jun 13. doi: 10.1136/bcr-2013-009701.
分子式 C6H12N4 |
分子量 140.19 |
CAS号 100-97-0 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 28 mg/mL |
Water <1 mg/mL |
Ethanol 9 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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