Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] M Sköld,et al. Ornidazole: a new antiprotozoal compound for treatment of Trichomonas vaginalis infection. Br J Vener Dis. 1977 Feb; 53(1): 44–48.
[2] Ellie J. C. Goldstein,et al. Comparative Susceptibilities of Anaerobic Bacteria to Metronidazole, Ornidazole, and SC-28538. Antimicrob Agents Chemother. 1978 Oct; 14(4): 609–613.
分子式 C7H10ClN3O3 |
分子量 219.63 |
CAS号 16773-42-5 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 200 mM |
Water 10 mM |
Ethanol 200 mM |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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