Pyridoxine HCl is a form of vitamin B6.
Pyridoxine HCl is a form of vitamin B6.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Michelle C. Potter,et al. Glutamate Carboxypeptidase II Inhibition Behaviorally and Physiologically Improves Pyridoxine-Induced Neuropathy in Rats. PLoS One. 2014; 9(9): e102936. Published online 2014 Sep 25. doi: 10.1371/journal.pone.0102936.
[2] Liping Xieet al. Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signalling pathway in human umbilical vein endothelial cells. Br J Pharmacol. 2012 Feb; 165(3): 754–764. doi: 10.1111/j.1476-5381.2011.01607.x.
分子式 C8H12ClNO3 |
分子量 205.64 |
CAS号 58-56-0 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO >40 mg/mL |
Water >40 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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