Enrofloxacin is a fluoroquinolone antibiotic.
Enrofloxacin is a fluoroquinolone antibiotic.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] K. KuKanich,et al. Effect of Sucralfate on the Relative Bioavailability of Enrofloxacin and Ciprofloxacin in Healthy Fed Dogs. J Vet Intern Med. 2016 Jan-Feb; 30(1): 108–115. Published online 2015 Dec 9. doi: 10.1111/jvim.13796.
[2] Annemarie Brauser,et al. Modulation of enrofloxacin binding in OmpF by Mg2+ as revealed by the analysis of fast flickering single-porin current. J Gen Physiol. 2012 Jul; 140(1): 69–82. doi: 10.1085/jgp.201210776.
分子式 C19H22FN3O3 |
分子量 359.39 |
CAS号 93106-60-6 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 3 mg/mL warmed |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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