Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM
Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Saritha Alladi and Nalini R Shastri. Semi solid matrix formulations of meloxicam and tenoxicam: an in vitro and in vivo evaluation. Archives of Pharmacal Research, 38(5), 801-812 (2015).
[2] Hakan Arslan et. Al. Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial. Journal of Oral Science, 53(2), 157-161 (2011).
分子式 C13H11N3O4S2 |
分子量 337.37832 |
CAS号 59804-37-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 60 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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