Sorbitol is a sugar alcohol and a sugar substitute.
Sorbitol is a sugar alcohol and a sugar substitute.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Ilya Chumakov et. Al. Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy. Orphanet Journal of Rare Diseases, 9(1), 201 (2014).
[2] Sinjan Choudhary et. Al. Inhibition of insulin fibrillation by osmolytes: Mechanistic insights. Scientific reports, 5, 17599 (2015).
分子式 C6H14O6 |
分子量 182.17 |
CAS号 50-70-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 36 mg/mL |
Water 36 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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