Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Jie Qu,et al. Rutin protects against cognitive deficits and brain damage in rats with chronic cerebral hypoperfusion. Br J Pharmacol. 2014 Aug; 171(15): 3702–3715. Published online 2014 Jul 17. doi: 10.1111/bph.12725.
[2] Carlos Frederico Lima Gonçalves,et al. Flavonoid Rutin Increases Thyroid Iodide Uptake in Rats. PLoS One. 2013; 8(9): e73908. Published online 2013 Sep 4. doi: 10.1371/journal.pone.0073908.
[3] Sangjin Seo,et al. Rutin Increases Muscle Mitochondrial Biogenesis with AMPK Activation in High-Fat Diet-Induced Obese Rats. Nutrients. 2015 Sep; 7(9): 8152–8169. Published online 2015 Sep 22. doi: 10.3390/nu7095385.
分子式 C27H30O16 |
分子量 610.52 |
CAS号 153-18-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 120 mg/mL |
Water <1 mg/mL |
Ethanol 2 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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