Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.
Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Jay P Patel et. Al. Measurement of Postreplicative DNA Metabolism and Damage in the Rodent Brain. Chemical Research in Toxicology, 28(12), 2352-2363 (2015).
[2] Monika Feigenbutz et. Al. The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae. PLoS ONE, 8(11), e80752 (2013).
分子式 C5H4N2O4 |
分子量 156.1 |
CAS号 65-86-1 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 2 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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