Bromhexine hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm.
Bromhexine hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Tatsuhiro Tsujimoto et. Al. Effect of bromhexine hydrochloride therapy for alcoholic chronic pancreatitis. Alcoholism: Clinical and Experimental Research, 29(12 Suppl), 272S-276S (2005).
[2] Ryusuke Kajihara et. Al. Structural changes of polymer-coated microgranules and excipients on tableting investigated by microtomography using synchrotron X-ray radiation. International Journal of Pharmaceutics, 481(1-2), 132-139 (2015).
[3] Matthew E Spector et. Al. Matted nodes: poor prognostic marker in oropharyngeal squamous cell carcinoma independent of HPV and EGFR status. Head & Neck (Print Edition), 34(12), 1727-1733 (2012).
分子式 C14H21Br2ClN2 |
分子量 412.59 |
CAS号 611-75-6 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 6 mg/mL |
Water <1 mg/mL |
Ethanol 5 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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