Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.
Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Kate S Collison et. Al. Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity. PLoS ONE, 7(4), e31570 (2012).
[2] Jaewon Shim et. Al. Modulation of sweet taste by umami compounds via sweet taste receptor subunit hT1R2. PLoS ONE, 10(4), e0124030 (2015).
分子式 C14H18N2O5 |
分子量 294.3 |
CAS号 22839-47-0 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO >30 mg/mL |
Water 4 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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