Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.
Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Arunoday Bhan,et al. Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo. J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2015 May 1. Published in final edited form as: J Steroid Biochem Mol Biol. 2014 May; 141: 160–170. Published online 2014 Feb 14. doi: 10.1016/j.jsbmb.2014.02.002.
[2] Pierre Bigot,et al. Quantitative proteomic determination of diethylstilbestrol action on prostate cancer. Asian J Androl. 2013 May 6; 15(3): 413–420. Published online 2013 Feb 25. doi: 10.1038/aja.2012.128.
分子式 C18H20O2 |
分子量 268.35 |
CAS号 56-53-1 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 54 mg/mL |
Water <1 mg/mL |
Ethanol 54 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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