Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Ronald E. Blanton,et al. Oxfendazole Treatment for Cystic Hydatid Disease in Naturally Infected Animals. Antimicrob Agents Chemother. 1998 Mar; 42(3): 601–605.
[2] Cesar M. Gavidia,et al. PLoS Negl Trop Dis. 2010 Feb; 4(2): e616. Published online 2010 Feb 23. doi: 10.1371/journal.pntd.0000616Evaluation of Oxfendazole, Praziquantel and Albendazole against Cystic Echinococcosis: A Randomized Clinical Trial in Naturally Infected Sheep.
分子式 C15H13N3O3S |
分子量 315.35 |
CAS号 53716-50-0 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 10 mg/mL |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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