Erdosteine is a mucolytic which is used in treatment of excessive viscous mucus.
Erdosteine is a mucolytic which is used in treatment of excessive viscous mucus.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Tunay Kurtoglu,et al. Erdosteine ameliorates lung injury induced by transient aortic occlusion in rats. Us, Ahmet Turan YilmazCardiovasc J Afr. 2007 Nov-Dec; 18(6): 367–370.
[2] Sami Karapolat,et al. Prevention of Pulmonary Complications of Pneumoperitoneum in Rats. J Cardiothorac Surg. 2011; 6: 14. Published online 2011 Feb 8. doi: 10.1186/1749-8090-6-14
分子式 C8H11NO4S2 |
分子量 249.31 |
CAS号 84611-23-4 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 50 mg/mL |
Water <1 mg/mL |
Ethanol 10 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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